Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.62 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 2/20 | 0.42 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24265586 | 1.00 | NR1H2 (0.62) | NR1H2ESR2ABHD6NPC1RAB9A | |
| SCHEMBL1263385 | 0.95 | ESR2 (0.63) | NR1H2ESR2ABHD6NPC1RAB9A | |
| SCHEMBL29587073 | 0.92 | NR1H2 (0.72) | NR1H2ESR2ABHD6NPC1RAB9A | |
| SCHEMBL1011003 | 0.92 | NR1H2 (0.72) | NR1H2ESR2ABHD6NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL38653092 | 0.91 | NR1H2 (0.70) | NR1H2ESR2ABHD6NPC1RAB9A | |
| SCHEMBL587847 | 0.87 | ESR2 (0.74) | NR1H2ESR2ABHD6NPC1RAB9A | |
| SCHEMBL29528794 | 0.87 | ESR2 (0.74) | NR1H2ESR2ABHD6NPC1RAB9A | |
| SCHEMBL30951607 | 0.86 | ABHD6 (0.60) | NR1H2ESR2ABHD6HDAC1MAPK1 | |
| SCHEMBL330056 | 0.86 | ABHD6 (0.60) | NR1H2ESR2ABHD6HDAC1MAPK1 | |
| SCHEMBL1648703 | 0.86 | ESR2 (0.76) | NR1H2ESR2ABHD6NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116507326-A | Compounds as GLP-1R agonists | 拓臻制药公司 | 2023-07-28 | — | — | CN | disclosed |
| EP-4199919-A1 | COMPOUNDS AS GLP-1R AGONISTS | Terns Pharmaceuticals, Inc. (US) | 2023-06-28 | — | — | EP | disclosed |
| WO-2022040600-A1 | COMPOUNDS AS GLP-1R AGONISTS | TERNS PHARMACEUTICALS, INC. (US) | 2022-02-24 | — | — | WO | disclosed |