SCHEMBL29574253

SCHEMBL29574253

O=C(C1=NOC(Cc2ccccc2)C1)c1ccc(Cl)cc1

nearest known ligand 0.59

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2C19 P33261 1/20 0.47
KMT2A Q03164 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL892050 0.81 LMNA (0.53)
SCHEMBL2918925 0.74
SCHEMBL892286 0.73 ALDH1A1 (0.58) CYP2C19
SCHEMBL6448155 0.70 LMNA (0.51)
SCHEMBL11627680 0.69 HDAC3 (0.48)
SCHEMBL11627603 0.69 HDAC3 (0.48)
SCHEMBL904384 0.69
SCHEMBL19194382 0.68 PPARG (0.47) CYP2C19
SCHEMBL1830918 0.68 LMNA (0.49) KMT2A
SCHEMBL10584373 0.67 ALDH1A1 (0.38) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108947924-B Preparation method and application of dihydroisoxazole benzophenone derivative and dihydroisoxazole benzophenone derivative 石河子大学 2022-05-10 CN claimed
CN-108947924-B Preparation method and application of dihydroisoxazole benzophenone derivative and dihydroisoxazole benzophenone derivative 石河子大学 2022-05-10 CN disclosed