Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 8/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696600 | 1.00 | DGAT1 (0.46) | DGAT1PDPK1AKR1B1P2RX7KMT2A | |
| SCHEMBL538344 | 0.85 | DGAT1 (0.55) | DGAT1PDPK1AKR1B1P2RX7KMT2A | |
| SCHEMBL31551664 | 0.85 | DGAT1 (0.55) | DGAT1PDPK1AKR1B1P2RX7KMT2A | |
| SCHEMBL2588909 | 0.85 | DGAT1 (0.42) | DGAT1PDPK1AKR1B1KMT2AMEN1 | |
| SCHEMBL16070101 | 0.85 | DGAT1 (0.46) | DGAT1PDPK1AKR1B1P2RX7KMT2A | |
| SCHEMBL29574729 | 0.83 | AKR1B1 (0.52) | DGAT1PDPK1AKR1B1P2RX7KMT2A | |
| SCHEMBL5835 | 0.83 | AKR1B1 (0.52) | DGAT1PDPK1AKR1B1P2RX7KMT2A | |
| SCHEMBL3515626 | 0.82 | PDPK1 (0.56) | DGAT1PDPK1AKR1B1P2RX7KMT2A | |
| SCHEMBL12501525 | 0.82 | DGAT1 (0.43) | DGAT1PDPK1AKR1B1P2RX7KMT2A | |
| SCHEMBL8444 | 0.81 | DGAT1 (0.46) | DGAT1PDPK1AKR1B1P2RX7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112867712-B | Carboxamide as ubiquitin-specific protease inhibitor | 瓦洛早期发现股份有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-116507326-A | Compounds as GLP-1R agonists | 拓臻制药公司 | 2023-07-28 | — | — | CN | disclosed |
| EP-4199919-A1 | COMPOUNDS AS GLP-1R AGONISTS | Terns Pharmaceuticals, Inc. (US) | 2023-06-28 | — | — | EP | disclosed |
| WO-2022040600-A1 | COMPOUNDS AS GLP-1R AGONISTS | TERNS PHARMACEUTICALS, INC. (US) | 2022-02-24 | — | — | WO | disclosed |