SCHEMBL29575136

SCHEMBL29575136

CC=COC[C@]1(C)O[C@H]2C[C@@]34C[C@H](C(C)(C)[C@@H]3CC[C@H]4C)[C@@]2(C)O1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ ALOX15 P16050 2/20 0.34
▸ ALDH1A1 P00352 1/20 0.34
▸ LMNA P02545 1/20 0.34
▸ THRB P10828 1/20 0.34
▸ MAPK1 P28482 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29575327 1.00 ALOX15 (0.34) ALOX15ALDH1A1LMNATHRBMAPK1
SCHEMBL29574773 1.00 ALOX15 (0.34) ALOX15ALDH1A1LMNATHRBMAPK1
SCHEMBL17637288 0.84 ALOX15 (0.38) ALOX15ALDH1A1LMNATHRBMAPK1
SCHEMBL22716568 0.84 ALOX15 (0.38) ALOX15ALDH1A1LMNATHRBMAPK1
SCHEMBL17637290 0.84 ALOX15 (0.38) ALOX15ALDH1A1LMNATHRBMAPK1
SCHEMBL22716433 0.81 ALOX15 (0.33) ALOX15ALDH1A1LMNATHRBMAPK1
SCHEMBL10086035 0.80 ALOX15 (0.40) ALOX15ALDH1A1LMNATHRBMAPK1
SCHEMBL29574926 0.80 ALOX15 (0.45) ALOX15ALDH1A1LMNATHRBMAPK1
SCHEMBL29574911 0.79 ALOX15 (0.42) ALOX15ALDH1A1LMNATHRBMAPK1
SCHEMBL34462111 0.78 ALOX15 (0.38) ALOX15ALDH1A1LMNATHRBMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3883927-B1 AMBER ODORANT FIRMENICH & CIE (CH) 2025-10-01 — — EP disclosed
US-12139469-B2 Amber odorant FIRMENICH SA (CH) 2024-11-12 — — US disclosed
US-20220106285-A1 AMBER ODORANT FIRMENICH SA (CH) 2022-04-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220106285-A1 AMBER ODORANT OPRM1, TRPA1, PYM1 ALOX15 423/4885ALDH1A1 860/4885LMNA 1634/4885
US-12139469-B2 Amber odorant OPRM1, TRPA1, PYM1 ALOX15 423/4885ALDH1A1 860/4885LMNA 1634/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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