SCHEMBL2957657

SCHEMBL2957657

C=C(C)C(=O)OC(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)C(F)F

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28552396 1.00 ALDH1A1 (0.31) ALDH1A1TSHR
SCHEMBL712582 1.00 ALDH1A1 (0.31) ALDH1A1TSHR
SCHEMBL28546850 1.00 ALDH1A1 (0.31) ALDH1A1TSHR
SCHEMBL285649 0.98 ALDH1A1 (0.32) ALDH1A1TSHR
SCHEMBL1369441 0.95 ALDH1A1 (0.32) ALDH1A1TSHR
SCHEMBL28221199 0.92
SCHEMBL28396878 0.91
SCHEMBL7106328 0.91
SCHEMBL16504611 0.91
SCHEMBL373093 0.91

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11186731-B2 Slippery self-lubricating polymer surfaces PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2021-11-30 US claimed
EP-3520861-A1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR Living Proof, Inc. (US) 2019-08-07 EP claimed
EP-2205196-B1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR LIVING PROOF INC (US) 2018-12-26 EP claimed
US-20180327608-A1 SLIPPERY SELF-LUBRICATING POLYMER SURFACES PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2018-11-15 US claimed
US-20170340545-A1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR LIVING PROOF INC (US) 2017-11-30 US claimed
US-9770399-B2 Hair care compositions and methods of treating hair LIVING PROOF, INC. (US) 2017-09-26 US claimed
US-20130336913-A1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR LIVING PROOF, INC. (US) 2013-12-19 US claimed
US-20100278769-A1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR LIVING PROOF, INC. (US) 2010-11-04 US claimed
US-20090104136-A1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR USING SAME LIVING PROOF, INC. 2009-04-23 US claimed
WO-2024086390-A9 CONTROLLABLE SLIPPERY POLYMER SURFACES PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2024-07-18 WO disclosed
US-12037463-B2 Antimicrobial ophthalmic devices comprising polysiloxane-polyglycerol block copolymers and methods of making and use thereof Clearlab Sg Pte Ltd. (SG) 2024-07-16 US disclosed
US-12024597-B2 Wound dressings comprising polysiloxane-polyglycerol block copolymers and methods of making and use thereof Clearlab Sg Pte Ltd. (SG) 2024-07-02 US disclosed
EP-2872572-B1 SLIPPERY SELF-LUBRICATING POLYMER SURFACES HARVARD COLLEGE (US) 2024-06-19 EP disclosed
WO-2024086390-A2 CONTROLLABLE SLIPPERY POLYMER SURFACES PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2024-04-25 WO disclosed
US-5929201-A A POLYAMIC ACID IS THE REACTION PRODUCT OF A FLUORINATED MONOAMINE, A DIAMINE AND ATLEAST ONE TETERACARBOXYLIC DIANHYDRIDE ELSICON, INC. (US) 1999-07-27 US disclosed
EP-0890131-A2 PROCESS AND MATERIALS FOR INDUCING PRE-TILT IN LIQUID CRYSTALS AND LIQUID CRYSTAL DISPLAYS ALLIANT TECHSYSTEMS INC. (US) 1999-01-13 EP disclosed
US-5822489-A CLADDING ON OPTICAL FIBER MADE OF A CURED MATERIAL COMPRISING A PERFLUOROPOLYETHER OR PERFLUOROHYDROCARBON BACKBONE END CAPPED WITH (METH)ACRYLATE GROUPS VIA URETHANE GROUPS LUCENT TECHNOLOGIES, INC. (US) 1998-10-13 US disclosed
EP-0851246-A1 Optical fiber clad with low refractive index photocured composition LUCENT TECHNOLOGIES INC. (US) 1998-07-01 EP disclosed
US-5731405-A POLYIMIDE COPOLYMER MADE FROM DIARYL KETONE TETRACARBOXYLIC DIANHYDRIDE, HYDROPHOBIC DIAMINE, AND ALICYCLIC TETRACARBOXYLIC ANHYDRIDE REACTANTS ALLIANT TECHSYSTEMS INC. (US) 1998-03-24 US disclosed
WO-1997037273-A2 PROCESS AND MATERIALS FOR INDUCING PRE-TILT IN LIQUID CRYSTALS AND LIQUID CRYSTAL DISPLAYS ALLIANT TECHSYSTEMS INC. (US) 1997-10-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100278769-A1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR FLNA, FLNB, FGF1 ALDH1A1 1490/4885TSHR 1808/4885
US-20170340545-A1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR FLNA, FLNB, FGF1 ALDH1A1 1490/4885TSHR 1808/4885
US-20130336913-A1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR FLNA, FLNB, FGF1 ALDH1A1 1490/4885TSHR 1808/4885
US-20090104136-A1 HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR USING SAME TET1, TET2, TET3 ALDH1A1 457/4885TSHR 3749/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.