Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29576693 | 0.87 | ESR1 (0.34) | GAAMAPTL3MBTL1KDM4E | |
| SCHEMBL29577461 | 0.87 | CTSL (0.36) | GBA1GAAMAPTL3MBTL1KDM4E | |
| SCHEMBL29578315 | 0.84 | PDE2A (0.38) | GAAMAPT | |
| SCHEMBL29577530 | 0.83 | IDO1 (0.36) | GBA1CYP1A2 | |
| SCHEMBL29576840 | 0.83 | GBA1 (0.39) | GBA1GAAMAPTL3MBTL1KDM4E | |
| SCHEMBL29576826 | 0.82 | GAA (0.32) | GAAMAPTL3MBTL1KDM4E | |
| SCHEMBL29577376 | 0.81 | GAA (0.32) | GAAMAPTL3MBTL1KDM4ELMNA | |
| SCHEMBL29578303 | 0.81 | NAMPT (0.36) | GAAMAPTL3MBTL1KDM4ELMNA | |
| SCHEMBL29577028 | 0.81 | LTC4S (0.36) | GAAMAPTL3MBTL1KDM4E | |
| SCHEMBL29577153 | 0.81 | CTSL (0.35) | GAAMAPTL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108558841-B | 4- (N, N-disubstituted) furan-2 (5H) -ketone derivative, preparation method and application thereof | 贵州大学 | 2022-04-12 | — | — | CN | claimed |