Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.35 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.33 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.33 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29576842 | 0.92 | KCNQ3 (0.34) | CTSLKCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL29577209 | 0.92 | KCNQ3 (0.34) | CTSLKCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL29576922 | 0.92 | CTSL (0.34) | CTSLKCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL29577376 | 0.90 | GAA (0.32) | CTSLMDM2GAAMAPTHDAC1 | |
| SCHEMBL29576799 | 0.90 | CTSL (0.33) | CTSLKCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL29577530 | 0.90 | IDO1 (0.36) | CTSLMDM2 | |
| SCHEMBL29577147 | 0.88 | OXTR (0.39) | CTSLMDM2GAAMAPT | |
| SCHEMBL29576693 | 0.86 | ESR1 (0.34) | KCNQ3KCNQ2KCNE1KCNQ1MDM2 | |
| SCHEMBL29577987 | 0.86 | MDM2 (0.31) | CTSLMDM2GAAMAPT | |
| SCHEMBL29577028 | 0.85 | LTC4S (0.36) | GAAMAPTKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108558841-B | 4- (N, N-disubstituted) furan-2 (5H) -ketone derivative, preparation method and application thereof | 贵州大学 | 2022-04-12 | — | — | CN | claimed |