Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28729454 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2TSHRUBE2TADORA2ACA12 | |
| SCHEMBL13479765 | 0.79 | TSHR (0.55) | SMN1; SMN2TSHRUBE2TMAPTKDM4E | |
| SCHEMBL20027612 | 0.77 | KDM5A (0.43) | TSHRKDM4EGAAP4HTMALDH1A1 | |
| SCHEMBL959286 | 0.74 | ALDH1A1 (0.51) | SMN1; SMN2TSHRUBE2TMAPTKDM4E | |
| SCHEMBL3461571 | 0.74 | MAPT (0.56) | SMN1; SMN2TSHRUBE2TADORA2AMAPT | |
| SCHEMBL20027608 | 0.74 | KDM4E (0.42) | SMN1; SMN2TSHRKDM4EALDH1A1RAB9A | |
| SCHEMBL20028517 | 0.72 | ALDH1A1 (0.51) | SMN1; SMN2TSHRMAPTKDM4EGAA | |
| SCHEMBL2891461 | 0.71 | HTT (0.51) | SMN1; SMN2TSHRUBE2TMAPTKDM4E | |
| SCHEMBL46302 | 0.70 | UBE2T (0.60) | SMN1; SMN2TSHRUBE2TMAPTKDM4E | |
| SCHEMBL13600098 | 0.70 | CA12 (0.44) | TSHRCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114292234-B | Preparation method of pyrazole derivative | 南方海洋科学与工程广东省实验室(湛江) | 2024-05-14 | — | — | CN | disclosed |
| CN-114292234-A | Preparation method of pyrazole derivative | 南方海洋科学与工程广东省实验室(湛江) | 2022-04-08 | — | — | CN | disclosed |