Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.47 |
| ▸ | CCR1 | P32246 | 1/20 | 0.47 |
| ▸ | CCR5 | P51681 | 1/20 | 0.47 |
| ▸ | CCR8 | P51685 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | KDM5A | P29375 | 2/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15764340 | 0.84 | CCR1 (0.52) | ALDH1A1LMNAMAPK10SMN1; SMN2CASP3 | |
| SCHEMBL3461571 | 0.78 | MAPT (0.56) | ALDH1A1LMNAMAPK10SMN1; SMN2PKM | |
| SCHEMBL46302 | 0.74 | UBE2T (0.60) | ALDH1A1LMNAMAPK10SMN1; SMN2CASP3 | |
| SCHEMBL29577243 | 0.74 | SMN1; SMN2 (0.50) | ALDH1A1LMNAMAPK10SMN1; SMN2CASP3 | |
| SCHEMBL28729454 | 0.74 | SMN1; SMN2 (0.50) | ALDH1A1LMNAMAPK10SMN1; SMN2CASP3 | |
| SCHEMBL19100367 | 0.74 | MAPT (0.51) | ALDH1A1LMNAMAPK10SMN1; SMN2CASP3 | |
| SCHEMBL15886685 | 0.73 | SMN1; SMN2 (0.62) | ALDH1A1LMNAMAPK10SMN1; SMN2CASP3 | |
| SCHEMBL27681222 | 0.73 | IRAK4 (0.47) | ALDH1A1LMNAMAPK10SMN1; SMN2CASP3 | |
| SCHEMBL31667857 | 0.73 | CCR1 (0.45) | ALDH1A1LMNASMN1; SMN2PKMMAPT | |
| SCHEMBL6619720 | 0.72 | ALDH1A1 (0.57) | ALDH1A1LMNASMN1; SMN2PKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2678346-B9 | METAL COMPLEXES FOR USE AS DOPANTS AND OTHER USES | ECOLE POLYTECHNIQUE FED LAUSANNE EPFL (CH) | 2018-08-08 | — | — | EP | disclosed |
| US-10038150-B2 | Metal complexes for use as dopants and other uses | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2018-07-31 | — | — | US | disclosed |
| EP-2678346-B1 | METAL COMPLEXES FOR USE AS DOPANTS AND OTHER USES | ECOLE POLYTECHNIQUE FED LAUSANNE EPFL (CH) | 2018-04-04 | — | — | EP | disclosed |
| US-9559321-B2 | Metal complexes for use as dopants and other uses | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2017-01-31 | — | — | US | disclosed |
| US-20160233439-A1 | METAL COMPLEXES FOR USE AS DOPANTS AND OTHER USES | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) EPFL-TTO (CH) | 2016-08-11 | — | — | US | disclosed |
| EP-2250998-B1 | SKIN WHITENING AGENT AND EXTERNAL PREPARATION FOR THE SKIN | SHISEIDO CO LTD (JP) | 2016-04-13 | — | — | EP | disclosed |
| CN-103492401-A | Metal complexes for use as dopants and other uses | ECOLE POLYTECH | 2014-01-01 | — | — | CN | disclosed |
| US-20130330632-A1 | METAL COMPLEXES FOR USE AS DOPANTS AND OTHER USES | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2013-12-12 | — | — | US | disclosed |
| US-8563552-B2 | Whitening agent and skin external preparation | SHISEIDO COMPANY LTD. (JP) | 2013-10-22 | — | — | US | disclosed |
| CN-101938988-B | Skin whitening agent and external preparation for the skin | SHISEIDO CO LTD | 2013-06-19 | — | — | CN | disclosed |
| EP-2212323-B1 | IMIDAZO [1,2-A] PYRIDINE DERIVATIVES USEFUL AS ALK INHIBITORS | NOVARTIS AG (CH) | 2012-08-15 | — | — | EP | disclosed |
| US-20110003817-A1 | Whitening Agent And Skin External Preparation | SHISEIDO COMPANY LTD. (JP) | 2011-01-06 | — | — | US | disclosed |
| EP-2250998-A1 | SKIN WHITENING AGENT AND EXTERNAL PREPARATION FOR THE SKIN | Shiseido Company, Ltd. (JP) | 2010-11-17 | — | — | EP | disclosed |
| US-20100210641-A1 | Organic Compounds | NOVARTIS AG (CH) | 2010-08-19 | — | — | US | disclosed |
| US-20100210641-A1 | Organic Compounds | NOVARTIS AG (CH) | 2010-08-19 | — | — | US | disclosed |
| US-7579348-B2 | Derivatives of 8-substituted xanthines | PGXHEALTH, LLC (US) | 2009-08-25 | — | — | US | disclosed |
| US-7579348-B2 | Derivatives of 8-substituted xanthines | PGXHEALTH, LLC (US) | 2009-08-25 | — | — | US | disclosed |
| WO-2009050183-A2 | IMIDAZO [1, 2-A] PYRIDINE DERIVATIVES USEFUL AS ALK INHIBITORS | NOVARTIS AG (CH) | 2009-04-23 | — | — | WO | disclosed |
| US-20070249598-A1 | Derivatives of 8-substituted xanthines | ADENOSINE THERAPEUTICS, LLC | 2007-10-25 | — | — | US | disclosed |
| US-20070249598-A1 | Derivatives of 8-substituted xanthines | ADENOSINE THERAPEUTICS, LLC | 2007-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100210641-A1 | Organic Compounds | ALK, ACVR1, ACVRL1 | ALDH1A1 1069/4885LMNA 1521/4885MAPK10 496/4885 |
| US-10038150-B2 | Metal complexes for use as dopants and other uses | SOD1, DDT, SOD3 | ALDH1A1 3311/4885LMNA 4465/4885MAPK10 2445/4885 |
| US-20110003817-A1 | Whitening Agent And Skin External Preparation | TYR, MC1R, RTN3 | ALDH1A1 1055/4885LMNA 679/4885MAPK10 2374/4885 |
| US-20160233439-A1 | METAL COMPLEXES FOR USE AS DOPANTS AND OTHER USES | SOD1, DDT, SOD3 | ALDH1A1 3311/4885LMNA 4465/4885MAPK10 2445/4885 |
| US-20070249598-A1 | Derivatives of 8-substituted xanthines | ADORA2B, ADORA2A, ADORA3 | ALDH1A1 940/4885LMNA 2265/4885MAPK10 3824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.