SCHEMBL29577889

SCHEMBL29577889

CSCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ NMBR P28336 2/20 0.61
▸ GRPR P30550 2/20 0.61
▸ CXCL8 P10145 9/20 0.59
▸ CTSL P07711 2/20 0.59
▸ CTSS P25774 2/20 0.59
▸ CTSK P43235 2/20 0.59
▸ CTSH P09668 1/20 0.59
▸ KISS1R Q969F8 1/20 0.57
▸ GLP1R P43220 3/20 0.57
▸ GCGR P47871 3/20 0.57
▸ F2 P00734 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29421992 0.87 CXCR4 (0.66) GRPRCXCL8KISS1RGLP1R
SCHEMBL29689766 0.87 CXCR4 (0.66) GRPRCXCL8KISS1RGLP1R
SCHEMBL31053728 0.87 KISS1R (0.56) NMBRGRPRCXCL8CTSLCTSS
SCHEMBL30432609 0.85 CXCR4 (0.67) NMBRGRPRCXCL8CTSLCTSS
SCHEMBL30072008 0.85 F2 (0.64) NMBRGRPRCXCL8KISS1RGLP1R
SCHEMBL29416123 0.85 CXCR4 (0.60) NMBRGRPRCXCL8KISS1RGLP1R
SCHEMBL30431758 0.85 C5AR1 (0.69) NMBRGRPRKISS1RGLP1RGCGR
SCHEMBL29663694 0.84 CXCL8 (0.59) NMBRGRPRCXCL8CTSLCTSS
SCHEMBL31000909 0.84 CXCL8 (0.64) CXCL8GLP1RGCGR
SCHEMBL30968310 0.84 GLP1R (0.68) NMBRGRPRGLP1RGCGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250381242-A1 ANTIMICROBIAL PEPTIDES AGAINST CITRUS GREENING INVAIO SCIENCES INC (US) 2025-12-18 — — US disclosed
US-20250382332-A1 NOVEL ALPHA-FACTOR BASED PEPTIDES WITH ANTIFUNGAL ACTIVITY INVAIO SCIENCES INC (US) 2025-12-18 — — US disclosed
US-20250287945-A1 COMPOSITIONS FOR FUNGAL CONTROL AND RELATED METHODS FLAGSHIP PIONEERING INNOVATIONS VII, LLC (US) 2025-09-18 — — US disclosed
US-20240368664-A1 LIVE YEAST BIOSENSORS AND METHODS OF USE THEREOF THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2024-11-07 — — US disclosed
EP-4373840-A1 COMPOSITIONS FOR FUNGAL CONTROL AND RELATED METHODS Flagship Pioneering Innovations VII, LLC (US) 2024-05-29 — — EP disclosed
EP-4352513-A2 LIVE YEAST BIOSENSORS AND METHODS OF USE THEREOF The Trustees Of Columbia University In The City Of New York (US) 2024-04-17 — — EP disclosed
US-11899014-B2 Detection of analytes using live cells THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2024-02-13 — — US disclosed
WO-2023004435-A1 COMPOSITIONS FOR FUNGAL CONTROL AND RELATED METHODS FLAGSHIP PIONEERING INNOVATIONS VII, LLC (US) 2023-01-26 — — WO disclosed
WO-2022246003-A2 LIVE YEAST BIOSENSORS AND METHODS OF USE THEREOF THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2022-11-24 — — WO disclosed
US-11473073-B2 Aminopeptidases for protein hydrolyzates DUPONT NUTRITION BIOSCIENCES APS (DK) 2022-10-18 — — US disclosed
US-20220119825-A1 SCALABLE PEPTIDE-GPCR INTERCELLULAR SIGNALING SYSTEMS THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2022-04-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220119825-A1 SCALABLE PEPTIDE-GPCR INTERCELLULAR SIGNALING SYSTEMS SCTR, GRPR, RGS8 NMBR 202/4885GRPR 2/4885CXCL8 755/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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