SCHEMBL29577987

SCHEMBL29577987

Fc1cc(F)c(CN(Cc2ccc(Cl)nc2)c2ccoc2)c(F)c1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MDM2 Q00987 1/20 0.31
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30
CTSL P07711 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29577023 0.89 GAA (0.33) GAAMAPT
SCHEMBL29576826 0.87 GAA (0.32) GAAMAPT
SCHEMBL29576693 0.87 ESR1 (0.34) MDM2GAAMAPT
SCHEMBL29577376 0.86 GAA (0.32) MDM2GAAMAPTCTSL
SCHEMBL29577153 0.86 CTSL (0.35) MDM2GAAMAPTCTSL
SCHEMBL29577209 0.85 KCNQ3 (0.34) GAAMAPTCTSL
SCHEMBL29576842 0.85 KCNQ3 (0.34) MDM2GAAMAPTCTSL
SCHEMBL29576922 0.85 CTSL (0.34) MDM2GAAMAPTCTSL
SCHEMBL29577149 0.84 GAA (0.40) GAAMAPT
SCHEMBL29577147 0.84 OXTR (0.39) MDM2GAAMAPTCTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108558841-B 4- (N, N-disubstituted) furan-2 (5H) -ketone derivative, preparation method and application thereof 贵州大学 2022-04-12 CN claimed