SCHEMBL29579355

SCHEMBL29579355

Nc1ccc(N)c(I)c1I

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 9/20 0.38
ALOX15 P16050 4/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
CASP1 P29466 1/20 0.38
CASP7 P55210 1/20 0.38
TDP1 Q9NUW8 5/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
THRB P10828 2/20 0.37
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA4 P22748 1/20 0.35
CA6 P23280 1/20 0.35
CA5A P35218 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
CA14 Q9ULX7 1/20 0.35
CA5B Q9Y2D0 1/20 0.35
ALDH1A1 P00352 6/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8543050 1.00 CYP3A4 (0.38) CYP3A4ALOX15SMN1; SMN2CASP1CASP7
SCHEMBL2250516 0.87 CA12 (0.34) CYP3A4ALOX15SMN1; SMN2CASP1CASP7
SCHEMBL23057309 0.82 CD44 (0.33) CYP3A4ALOX15SMN1; SMN2CASP1CASP7
SCHEMBL13573831 0.77
SCHEMBL1704559 0.76 KDM4E (0.35) CYP3A4SMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL8211215 0.74 TDP1 (0.43) CYP3A4ALOX15SMN1; SMN2TDP1MEN1
SCHEMBL5028771 0.74 KDM4E (0.48) CYP3A4ALOX15CASP1CASP7TDP1
SCHEMBL3772724 0.74 CA2 (0.46) TDP1MEN1KMT2ATHRBCA12
SCHEMBL3867828 0.73 ALDH1A1 (0.39) CA12CA1CA2CA4CA6
SCHEMBL9229801 0.73 CYP3A4 (0.39) CYP3A4ALOX15SMN1; SMN2CASP1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112301443-B Three-stage heat setting method of heterocyclic aramid fiber 中蓝晨光化工有限公司 2022-04-12 CN disclosed