Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | CDK9 | P50750 | 2/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | CAMK2D | Q13557 | 3/20 | 0.40 |
| ▸ | KMT5B | Q4FZB7 | 2/20 | 0.39 |
| ▸ | KMT5C | Q86Y97 | 2/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28253313 | 1.00 | CNR1 (0.49) | CNR1CDK9MAP4K4CNR2PLK1 | |
| SCHEMBL12339802 | 0.78 | MAPT (0.37) | CNR1CDK9PLK1MAPTCAMK2D | |
| SCHEMBL1467354 | 0.77 | ALDH1A1 (0.52) | CNR1CNR2MAPT | |
| SCHEMBL1467081 | 0.77 | USP30 (0.53) | CNR1CNR2 | |
| SCHEMBL3758806 | 0.76 | PLK1 (0.51) | PLK1MAPTCAMK2DMAPK8 | |
| SCHEMBL30668832 | 0.76 | JAK2 (0.61) | CDK9MAPTMALT1 | |
| SCHEMBL29131118 | 0.76 | JAK2 (0.61) | CDK9MAPTMALT1 | |
| SCHEMBL1030530 | 0.75 | ADORA1 (0.59) | MAP4K4CNR2PLK1ADORA1CAMK2D | |
| SCHEMBL3619159 | 0.75 | ADORA1 (0.59) | MAP4K4CNR2PLK1ADORA1CAMK2D | |
| SCHEMBL1028968 | 0.73 | MAP4K4 (0.55) | MAP4K4IKBKBRETMAPK8MAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108727368-B | Nitrogen-containing fused heterocyclic compound, preparation method, intermediate, composition and application thereof | 上海医药集团股份有限公司 | 2022-05-03 | — | — | CN | disclosed |