Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 10/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2599063 | 0.69 | MEN1 (0.44) | XDH | |
| SCHEMBL15280147 | 0.69 | PARG (0.32) | — | |
| SCHEMBL2734677 | 0.69 | MAPK8 (0.38) | — | |
| SCHEMBL30879089 | 0.66 | KDM4E (0.33) | — | |
| SCHEMBL17165115 | 0.65 | XDH (0.35) | XDH | |
| SCHEMBL6073718 | 0.61 | BACE1 (0.37) | — | |
| SCHEMBL29547282 | 0.61 | ADORA2A (0.34) | XDH | |
| SCHEMBL4219276 | 0.61 | ADORA2A (0.34) | XDH | |
| SCHEMBL15041837 | 0.61 | NOS3 (0.32) | — | |
| SCHEMBL5407960 | 0.60 | CYP1A2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591334-B | Dihydropyrazolopyrimidinone derivatives | 山东轩竹医药科技有限公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-115197221-A | Dihydropyrazolopyrimidinone macrocyclic derivatives and application thereof | 轩竹生物科技股份有限公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-114591334-A | Dihydropyrazolopyrimidinone derivatives | 山东轩竹医药科技有限公司 | 2022-06-07 | — | — | CN | disclosed |