Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | GFER | P55789 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22471194 | 1.00 | MAPT (0.50) | MAPTGFERALDH1A1KDM4EGAA | |
| SCHEMBL5832389 | 0.90 | MAPT (0.49) | MAPTGFERALDH1A1KDM4EGAA | |
| SCHEMBL25894890 | 0.89 | MAPT (0.50) | MAPTGFERALDH1A1KDM4EGAA | |
| SCHEMBL25895983 | 0.89 | MAPT (0.50) | MAPTGFERALDH1A1KDM4EGAA | |
| SCHEMBL1020852 | 0.84 | APP (0.41) | MAPTGFERALDH1A1KDM4EGAA | |
| SCHEMBL1570709 | 0.84 | MAPT (0.42) | MAPTGFERALDH1A1KDM4EGAA | |
| SCHEMBL24352935 | 0.83 | L3MBTL1 (0.41) | MAPTALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL6617770 | 0.82 | ADRB1 (0.42) | MAPTNPSR1SLC6A2SLC6A3 | |
| SCHEMBL30598251 | 0.82 | MAPT (0.44) | MAPTGFERALDH1A1KDM4EGAA | |
| SCHEMBL29914525 | 0.81 | LTA4H (0.35) | SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591334-B | Dihydropyrazolopyrimidinone derivatives | 山东轩竹医药科技有限公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-114591334-A | Dihydropyrazolopyrimidinone derivatives | 山东轩竹医药科技有限公司 | 2022-06-07 | — | — | CN | disclosed |