Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28548105 | 1.00 | MAPT (0.44) | MAPTALDH1A1CYP3A4GLACYP19A1 | |
| SCHEMBL28330461 | 0.83 | ALDH1A1 (0.42) | MAPTALDH1A1CYP3A4CYP19A1VCAM1 | |
| SCHEMBL4427422 | 0.81 | ALDH1A1 (0.46) | MAPTALDH1A1CYP19A1VCAM1MEN1 | |
| SCHEMBL27689229 | 0.74 | HTR1D (0.44) | MAPTALDH1A1CYP3A4CYP19A1VCAM1 | |
| SCHEMBL26694532 | 0.73 | ALDH1A1 (0.44) | MAPTALDH1A1CYP3A4GLACYP19A1 | |
| SCHEMBL1686017 | 0.71 | UHRF1 (0.40) | MAPTALDH1A1GLAMEN1KMT2A | |
| SCHEMBL395008 | 0.71 | PNMT (0.51) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29581896 | 0.71 | PNMT (0.51) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27670186 | 0.71 | ALDH1A1 (0.48) | MAPTALDH1A1CYP19A1VCAM1KMT2A | |
| SCHEMBL29698223 | 0.71 | PARP10 (0.50) | MAPTALDH1A1CYP3A4GLACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112574106-B | Synthesis method of 7-amino-5-bromoquinoline | 苏州康润医药有限公司 | 2022-04-12 | — | — | CN | claimed |
| CN-112574106-B | Synthesis method of 7-amino-5-bromoquinoline | 苏州康润医药有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-112574106-B | Synthesis method of 7-amino-5-bromoquinoline | 苏州康润医药有限公司 | 2022-04-12 | — | — | CN | disclosed |