SCHEMBL1686017

SCHEMBL1686017

Cc1cc(Br)c2c(c1)NCCC2

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
UHRF1 Q96T88 1/20 0.40
ALDH1A1 P00352 6/20 0.39
MAPT P10636 5/20 0.39
NUDT1 P36639 6/20 0.38
ATM Q13315 1/20 0.35
HSD17B10 Q99714 5/20 0.33
GAA P10253 4/20 0.33
LMNA P02545 3/20 0.33
KDM4E B2RXH2 3/20 0.33
CASP1 P29466 2/20 0.33
CASP7 P55210 2/20 0.33
GLA P06280 1/20 0.33
HPGD P15428 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
GRIA1 P42261 1/20 0.33
GRIA2 P42262 1/20 0.33
GRIA3 P42263 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31161619 0.89 ALDH1A1 (0.34) ALDH1A1MAPTHSD17B10GAALMNA
SCHEMBL5993417 0.82 UHRF1 (0.47) UHRF1ALDH1A1MAPTNUDT1ATM
SCHEMBL30471909 0.79 PARP1 (0.40) UHRF1ALDH1A1NUDT1KDM4ECA12
SCHEMBL25390183 0.79 PARP1 (0.40) UHRF1ALDH1A1NUDT1KDM4ECA12
SCHEMBL22312385 0.78 UHRF1 (0.40) UHRF1ALDH1A1MAPTNUDT1ATM
SCHEMBL5405723 0.77 UHRF1 (0.42) UHRF1ALDH1A1MAPTNUDT1ATM
SCHEMBL22435470 0.75 ALDH1A1 (0.38) UHRF1ALDH1A1MAPTNUDT1ATM
SCHEMBL1761215 0.72 UGT2B17 (0.36) UHRF1ALDH1A1MAPTNUDT1HSD17B10
SCHEMBL21187389 0.71 KDM4E (0.30) ALDH1A1MAPTHSD17B10GAAKDM4E
SCHEMBL28548105 0.71 MAPT (0.44) ALDH1A1MAPTLMNAGLACA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2147027-B1 LONG CHAIN-BRANCHED ETHYLENE-1-BUTENE COPOLYMER LG CHEMICAL LTD (KR) 2017-09-27 EP disclosed
US-8759466-B2 Long chain-branched ethylene-alpha olefin copolymer LG CHEM, LTD. (KR) 2014-06-24 US disclosed
US-8748547-B2 Ethylene α-olefin copolymer LG CHEM, LTD. (KR) 2014-06-10 US disclosed
US-8742049-B2 Long chain-branched ethylene-alpha olefin copolymer LG CHEM, LTD. (KR) 2014-06-03 US disclosed
US-20130317186-A1 LONG CHAIN-BRANCHED ETHYLENE-ALPHA OLEFIN COPOLYMER LG CHEM, LTD. (KR) 2013-11-28 US disclosed
US-20130317187-A1 LONG CHAIN-BRANCHED ETHYLENE-ALPHA OLEFIN COPOLYMER LG CHEM, LTD. (KR) 2013-11-28 US disclosed
EP-1999165-B9 TRANSITION METAL COMPLEX, CATALYST COMPOSITION INCLUDING THE SAME AND OLEFIN POLYMER USING CATALYST COMPOSITION LG CHEMICAL LTD (KR) 2013-09-11 EP disclosed
US-8513369-B2 Long chain-branched ethylene-alpha olefin copolymer LG CHEM, LTD. (KR) 2013-08-20 US disclosed
EP-1999165-B1 TRANSITION METAL COMPLEX, CATALYST COMPOSITION INCLUDING THE SAME AND OLEFIN POLYMER USING CATALYST COMPOSITION LG CHEMICAL LTD (KR) 2013-04-24 EP disclosed
US-8048973-B2 Transition metal complex, catalyst composition including the same and olefin polymer using catalyst composition LG CHEM, LTD. (KR) 2011-11-01 US disclosed
US-20110152529-A1 TRANSITION METAL COMPLEX, CATALYST COMPOSITION INCLUDING THE SAME AND OLEFIN POLYMER USING CATALYST COMPOSITION LG CHEM, LTD. (KR) 2011-06-23 US disclosed
US-7928256-B2 Transition metal complex, catalyst composition including the same and olefin polymer using catalyst composition LG CHEM, LTD. (KR) 2011-04-19 US disclosed
US-20100179291-A1 LONG CHAIN-BRANCHED ETHYLENE-ALPHA OLEFIN COPOLYMER LG CHEM, LTD. (KR) 2010-07-15 US disclosed
US-20100087609-A1 ETHYLENE ALPHA-OLEFIN COPOYMER LG CHEM, LTD. (KR) 2010-04-08 US disclosed
EP-2147027-A2 LONG CHAIN-BRANCHED ETHYLENE-ALPHA OLEFIN COPOLYMER LG Chem, Ltd. (KR) 2010-01-27 EP disclosed
EP-1999165-A1 TRANSITION METAL COMPLEX, CATALYST COMPOSITION INCLUDING THE SAME AND OLEFIN POLYMER USING CATALYST COMPOSITION LG Chem, Ltd. (KR) 2008-12-10 EP disclosed
WO-2008140205-A1 ETHYLENE ALPHA-OLEFIN COPOLYMER LG CHEM, LTD. (KR) 2008-11-20 WO disclosed
WO-2008140280-A2 LONG CHAIN-BRANCHED ETHYLENE-ALPHA OLEFIN COPOLYMER LG CHEM, LTD. (KR) 2008-11-20 WO disclosed
WO-2007111423-A1 TRANSITION METAL COMPLEX, CATALYST COMPOSITION INCLUDING THE SAME AND OLEFIN POLYMER USING CATALYST COMPOSITION LG CHEM, LTD. (KR) 2007-10-04 WO disclosed
US-20070225158-A1 Transition Metal Complex, Catalyst Composition Including the Same and Olefin Polymer Using Catalyst Composition LG CHEM, LTD. (KR) 2007-09-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070225158-A1 Transition Metal Complex, Catalyst Composition Including the Same and Olefin Polymer Using Catalyst Composition OSTC, MACO1, PORCN UHRF1 3999/4885ALDH1A1 4234/4885MAPT 1302/4885
US-20110152529-A1 TRANSITION METAL COMPLEX, CATALYST COMPOSITION INCLUDING THE SAME AND OLEFIN POLYMER USING CATALYST COMPOSITION OSTC, MACO1, PORCN UHRF1 3999/4885ALDH1A1 4234/4885MAPT 1302/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.