SCHEMBL7741924

SCHEMBL7741924

O=S(=O)(c1ccc(Cl)cc1)n1nnc2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 1.00
SLC9A1 P19634 2/20 0.77
ALDH3A1 P30838 4/20 0.56
TSHR P16473 4/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
CRHBP P24387 1/20 0.55
RECQL P46063 1/20 0.55
CRHR2 Q13324 1/20 0.55
HPGD P15428 2/20 0.55
LMNA P02545 1/20 0.55
HTT P42858 2/20 0.54
CXCL8 P10145 1/20 0.54
NOD2 Q9HC29 1/20 0.54
NOD1 Q9Y239 1/20 0.54
POLB P06746 1/20 0.53
ALDH1A1 P00352 2/20 0.52
HSD17B10 Q99714 3/20 0.52
GAA P10253 1/20 0.52
KMT2A Q03164 2/20 0.51
NPSR1 Q6W5P4 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2491809 0.87 SLC9A1 (1.00) CYP2C19SLC9A1TSHRSMN1; SMN2CRHBP
SCHEMBL29479875 0.87 SLC9A1 (1.00) CYP2C19SLC9A1TSHRSMN1; SMN2CRHBP
SCHEMBL2958185 0.85 SLC9A1 (0.97) CYP2C19SLC9A1TSHRSMN1; SMN2CRHBP
SCHEMBL27855467 0.84 CYP2C19 (0.73) CYP2C19SLC9A1ALDH3A1TSHRSMN1; SMN2
SCHEMBL7746353 0.84 SLC9A1 (1.00) CYP2C19SLC9A1ALDH3A1TSHRSMN1; SMN2
Ammonia Solution, Strong SCHEMBL3379015 0.83 SLC9A1 (0.85) CYP2C19SLC9A1TSHRSMN1; SMN2CRHBP
SCHEMBL7746984 0.81 SLC9A1 (0.72) CYP2C19SLC9A1TSHRSMN1; SMN2HPGD
SCHEMBL11439834 0.81 SLC9A1 (0.70) CYP2C19SLC9A1TSHRHPGDLMNA
SCHEMBL10541164 0.77 SMN1; SMN2 (0.67) CYP2C19SLC9A1TSHRSMN1; SMN2CRHBP
SCHEMBL18062179 0.76 SLC9A1 (0.64) CYP2C19SLC9A1TSHRSMN1; SMN2CRHBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6171767-B1 BLACK-AND-WHITE PHOTOTHERMOGRAPHIC ELEMENT WITH AN IMAGING COATING COMPRISING PHOTOSENSITIVE SILVER HALIDE, REDUCIBLE SILVER SOURCE, REDUCING AGENT, BINDER, BENZOTRIAZOLE COMPOUND EASTMAN KODAK COMPANY 2001-01-09 US disclosed
EP-1048975-A1 1-sulfonyl-1H-benzotriazole compounds as print stabilizers in photothermographic elements EASTMAN KODAK COMPANY (US) 2000-11-02 EP disclosed