Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 17/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 17/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 16/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 16/20 | 0.56 |
| ▸ | CLK4 | Q9HAZ1 | 10/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 8/20 | 0.56 |
| ▸ | TSHR | P16473 | 14/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 8/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.53 |
| ▸ | USP2 | O75604 | 6/20 | 0.53 |
| ▸ | APLNR | P35414 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1197180 | 0.86 | CYP1A2 (0.55) | CYP1A2CYP3A4CYP2D6CYP2C19CLK4 | |
| SCHEMBL30080224 | 0.85 | CYP1A2 (0.56) | CYP1A2CYP3A4CYP2D6CYP2C19CLK4 | |
| SCHEMBL24493287 | 0.84 | CYP1A2 (0.54) | CYP1A2CYP3A4CYP2D6CYP2C19CLK4 | |
| SCHEMBL29650033 | 0.84 | CYP1A2 (0.54) | CYP1A2CYP3A4CYP2D6CYP2C19CLK4 | |
| SCHEMBL31340133 | 0.84 | CYP1A2 (0.55) | CYP1A2CYP3A4CYP2D6CYP2C19CLK4 | |
| SCHEMBL319266 | 0.82 | APLNR (0.63) | CYP1A2CYP3A4CYP2D6CYP2C19CLK4 | |
| SCHEMBL1197943 | 0.81 | CYP1A2 (0.59) | CYP1A2CYP3A4CYP2D6CYP2C19CLK4 | |
| SCHEMBL17105218 | 0.80 | CYP1A2 (0.55) | CYP1A2CYP3A4CYP2D6CYP2C19CLK4 | |
| SCHEMBL30615467 | 0.80 | NPC1 (0.69) | CYP1A2CYP3A4CYP2D6CYP2C19CLK4 | |
| SCHEMBL4040609 | 0.80 | NPC1 (0.69) | CYP1A2CYP3A4CYP2D6CYP2C19CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11802120-B2 | Fused cyclic urea derivatives as CRHR2 antagonist | RAQUALIA PHARMA INC. (JP) | 2023-10-31 | — | — | US | disclosed |
| EP-3774739-B1 | FUSED CYCLIC UREA DERIVATIVES AS CRHR2 ANTAGONIST | RAQUALIA PHARMA INC (JP) | 2022-05-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11802120-B2 | Fused cyclic urea derivatives as CRHR2 antagonist | CRHR2, CRHR1, CRH | CYP1A2 3484/4885CYP3A4 4562/4885CYP2D6 4316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.