SCHEMBL29581990

SCHEMBL29581990

Cc1nn(C)c(=O)c(-c2c(F)ccc(Cl)c2CCc2ccc(C#N)cc2)c1O

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
AR P10275 4/20 0.36
CNR1 P21554 4/20 0.36
CCR3 P51677 1/20 0.35
NR3C1 P04150 1/20 0.34
CACNA1H O95180 1/20 0.34
ITGB1 P05556 1/20 0.33
ITGA4 P13612 1/20 0.33
ITGB7 P26010 1/20 0.33
MAPT P10636 1/20 0.33
MCL1 Q07820 2/20 0.32
MAPK14 Q16539 1/20 0.32
GPR139 Q6DWJ6 1/20 0.31
P2RX7 Q99572 1/20 0.31
DAO P14920 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22085783 1.00 AR (0.36) ARCNR1CCR3NR3C1CACNA1H
SCHEMBL22084636 0.90 LMNA (0.36) NR3C1MAPT
SCHEMBL22031854 0.89 CYP1A2 (0.38) ARMAPTP2RX7
SCHEMBL22031792 0.87 CASR (0.40) MAPTMCL1
SCHEMBL22085782 0.86 MAPT (0.37) CACNA1HMAPTP2RX7DAO
SCHEMBL22906239 0.85 MAPT (0.33) MAPT
SCHEMBL22084637 0.85 POLB (0.35) CNR1NR3C1MAPTMCL1DAO
SCHEMBL22906297 0.85 LMNA (0.40) ITGB1ITGA4ITGB7MAPT
SCHEMBL22906232 0.85 MAPT (0.33) MAPT
SCHEMBL22906269 0.85 CCR3 (0.33) ARCNR1CCR3NR3C1CACNA1H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12162840-B2 Herbicidal compositions SYNGENTA CROP PROTECTION AG (CH) 2024-12-10 US claimed
US-20230301300-A1 HERBICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2023-09-28 US claimed
US-20220119353-A1 Herbicidal Compositions SYNGENTA PARTICIPATIONS AG (CH) 2022-04-21 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12162840-B2 Herbicidal compositions DDT, HPD, PNPO AR 4726/4885CNR1 3230/4885CCR3 3601/4885
US-20230301300-A1 HERBICIDAL COMPOSITIONS GMDS, DDT, AADAC AR 4692/4885CNR1 2737/4885CCR3 4208/4885
US-20220119353-A1 Herbicidal Compositions DDT, HPD, PNPO AR 4726/4885CNR1 3230/4885CCR3 3601/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.