Methacrylic Acid

Methacrylic Acid

SCHEMBL29583152

C=C(C)C(=O)O.C=C(C)C(=O)O.C=C(C)C(=O)O.C=C(C)C(=O)OCCC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.47
THRB P10828 1/20 0.41
POLB P06746 1/20 0.40
APEX1 P27695 1/20 0.40
HTT P42858 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
ALDH1A1 P00352 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL15856026 1.00 TSHR (0.47) TSHRTHRBPOLBAPEX1HTT
SCHEMBL35807 0.95 TSHR (0.51) TSHRTHRBPOLBAPEX1HTT
SCHEMBL333002 0.94 TSHR (0.50) TSHRTHRBPOLBAPEX1HTT
Methacrylic Acid SCHEMBL29405654 0.93 TSHR (0.42) TSHRTHRBPOLBAPEX1HTT
SCHEMBL9418354 0.91 TSHR (0.47) TSHRTHRBPOLBAPEX1HTT
SCHEMBL11157535 0.91 TSHR (0.47) TSHRTHRBPOLBAPEX1HTT
SCHEMBL11312944 0.91 TSHR (0.47) TSHRTHRBPOLBAPEX1HTT
SCHEMBL11312974 0.91 TSHR (0.47) TSHRTHRBPOLBAPEX1HTT
SCHEMBL397519 0.90 TSHR (0.54) TSHRTHRBPOLBAPEX1HTT
Acrylic Acid SCHEMBL5820204 0.90 TSHR (0.44) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240184137-A1 CONTACT LENSES AND METHODS OF MAKING CONTACT LENSES UNIV FLORIDA (US) 2024-06-06 US claimed
WO-2022221259-A1 CONTACT LENSES AND METHODS OF MAKING CONTACT LENSES UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2022-10-20 WO claimed
US-20240184137-A1 CONTACT LENSES AND METHODS OF MAKING CONTACT LENSES UNIV FLORIDA (US) 2024-06-06 US disclosed
US-11826974-B2 Methods and compositions for pigmented hydrogels and contact lenses UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2023-11-28 US disclosed
WO-2022221259-A1 CONTACT LENSES AND METHODS OF MAKING CONTACT LENSES UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2022-10-20 WO disclosed
US-20220134694-A1 METHODS AND COMPOSITIONS FOR PIGMENTED HYDROGELS AND CONTACT LENSES UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2022-05-05 US disclosed
US-11260612-B2 Methods and compositions for pigmented hydrogels and contact lenses UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2022-03-01 US disclosed