SCHEMBL29583288

SCHEMBL29583288

Nc1nc2ccccc2c2ccccc12

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DCPS Q96C86 1/20 0.64
KDM4E B2RXH2 4/20 0.59
ALDH1A1 P00352 4/20 0.59
HPGD P15428 4/20 0.59
HSD17B10 Q99714 4/20 0.59
GAA P10253 2/20 0.59
MAPT P10636 2/20 0.59
SMN1; SMN2 Q16637 3/20 0.58
GLA P06280 2/20 0.58
CASP1 P29466 2/20 0.58
CASP7 P55210 2/20 0.58
ADORA3 P0DMS8 2/20 0.58
CHRM2 P08172 1/20 0.58
ADRA2A P08913 1/20 0.58
CHRM1 P11229 1/20 0.58
NQO2 P16083 1/20 0.58
MAOA P21397 1/20 0.58
DRD1 P21728 1/20 0.58
ACHE P22303 1/20 0.58
SLC6A2 P23975 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL72801 1.00 DCPS (0.64) DCPSKDM4EALDH1A1HPGDHSD17B10
SCHEMBL8628496 0.83 CLK1 (0.54) DCPSKDM4EALDH1A1HPGDHSD17B10
SCHEMBL3487308 0.82 KDM4E (0.50) DCPSKDM4EALDH1A1HPGDHSD17B10
SCHEMBL12733670 0.82 CLK1 (0.66) DCPSKDM4EALDH1A1HPGDHSD17B10
SCHEMBL1675370 0.82 CLK1 (0.66) DCPSKDM4EALDH1A1HPGDHSD17B10
SCHEMBL31061156 0.82 CLK1 (0.66) DCPSKDM4EALDH1A1HPGDHSD17B10
SCHEMBL8630481 0.81 MDM4 (0.47) DCPSKDM4EALDH1A1HPGDHSD17B10
SCHEMBL840416 0.80 CLK1 (0.51) DCPSKDM4EALDH1A1HPGDHSD17B10
SCHEMBL12733642 0.80 CLK1 (0.51) DCPSKDM4EALDH1A1HPGDHSD17B10
SCHEMBL71734 0.80 CLK1 (0.51) DCPSKDM4EALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3996697-A1 NOVEL PFAR-INHIBITING COMPOUNDS Université de Bretagne Occidentale (U.B.O.) (FR) 2022-05-18 EP claimed
US-12421537-B2 Ribosome variants for sequence defined polymer synthesis NORTHWESTERN UNIVERSITY (US) 2025-09-23 US disclosed
EP-4405369-A2 A CIS-PLATINUM(II)-OLIGOMER HYBRID Dublin City University (IE) 2024-07-31 EP disclosed
WO-2023046875-A2 A CIS-PLATINUM(II)-OLIGOMER HYBRID DUBLIN CITY UNIVERSITY (IE) 2023-03-30 WO disclosed
US-20220177941-A1 RIBOSOME VARIANTS FOR SEQUENCE DEFINED POLYMER SYNTHESIS NORTHWESTERN UNIVERSITY 2022-06-09 US disclosed
EP-3996697-A1 NOVEL PFAR-INHIBITING COMPOUNDS Université de Bretagne Occidentale (U.B.O.) (FR) 2022-05-18 EP disclosed