SCHEMBL72801

SCHEMBL72801

Nc1nc2ccccc2c2ccccc12

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DCPS Q96C86 1/20 0.64
KDM4E B2RXH2 4/20 0.59
ALDH1A1 P00352 4/20 0.59
HPGD P15428 4/20 0.59
HSD17B10 Q99714 4/20 0.59
GAA P10253 2/20 0.59
MAPT P10636 2/20 0.59
SMN1; SMN2 Q16637 3/20 0.58
GLA P06280 2/20 0.58
CASP1 P29466 2/20 0.58
CASP7 P55210 2/20 0.58
ADORA3 P0DMS8 2/20 0.58
CHRM2 P08172 1/20 0.58
ADRA2A P08913 1/20 0.58
CHRM1 P11229 1/20 0.58
NQO2 P16083 1/20 0.58
MAOA P21397 1/20 0.58
DRD1 P21728 1/20 0.58
ACHE P22303 1/20 0.58
SLC6A2 P23975 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29583288 1.00 DCPS (0.64) DCPSKDM4EALDH1A1HPGDHSD17B10
SCHEMBL8628496 0.83 CLK1 (0.54) DCPSKDM4EALDH1A1HPGDHSD17B10
SCHEMBL3487308 0.82 KDM4E (0.50) DCPSKDM4EALDH1A1HPGDHSD17B10
SCHEMBL12733670 0.82 CLK1 (0.66) DCPSKDM4EALDH1A1HPGDHSD17B10
SCHEMBL1675370 0.82 CLK1 (0.66) DCPSKDM4EALDH1A1HPGDHSD17B10
SCHEMBL31061156 0.82 CLK1 (0.66) DCPSKDM4EALDH1A1HPGDHSD17B10
SCHEMBL8630481 0.81 MDM4 (0.47) DCPSKDM4EALDH1A1HPGDHSD17B10
SCHEMBL840416 0.80 CLK1 (0.51) DCPSKDM4EALDH1A1HPGDHSD17B10
SCHEMBL12733642 0.80 CLK1 (0.51) DCPSKDM4EALDH1A1HPGDHSD17B10
SCHEMBL71734 0.80 CLK1 (0.51) DCPSKDM4EALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220273637-A1 NOVEL PFAR-INHIBITING COMPOUNDS Institut National de la Santé et de la Recherche Médicale (FR) 2022-09-01 US claimed
EP-3996697-A1 NOVEL PFAR-INHIBITING COMPOUNDS Université de Bretagne Occidentale (U.B.O.) (FR) 2022-05-18 EP claimed
WO-2021005189-A1 NOVEL PFAR-INHIBITING COMPOUNDS UNIVERSITE DE BRETAGNE OCCIDENTALE (UBO) (FR) 2021-01-14 WO claimed
US-12421537-B2 Ribosome variants for sequence defined polymer synthesis NORTHWESTERN UNIVERSITY (US) 2025-09-23 US disclosed
WO-2025113647-A3 PHENANTHRIDIN-6-AMINES FOR USE IN THE TREATMENT OF CANCERS EXPRESSING EBV ANTIGENS SCIENTIAM PHARMA (FR) 2025-06-26 WO disclosed
WO-2025113647-A2 HETEROCYCLIC DERIVATIVES AND THEIR USE IN THE TREATMENT OR THE PREVENTION OF EBV-ASSOCIATED DISORDERS SCIENTIAM PHARMA (FR) 2025-06-05 WO disclosed
EP-3782649-B1 BIODEGRADABLE POLYETHYLENE GLYCOL BASED WATER-INSOLUBLE HYDROGELS ASCENDIS PHARMA AS (DK) 2025-05-14 EP disclosed
US-20240382602-A1 A CIS-PLATINUM(II)-OLIGOMER HYBRID DUBLIN CITY UNIVERSITY (IE) 2024-11-21 US disclosed
CN-118103385-A Cis-platinum (II) oligomer hybrids 都柏林城市大学 2024-05-28 CN disclosed
US-20230381323-A1 RELEASABLE CONJUGATES FISH & RICHARDSON PC 2023-11-30 US disclosed
US-11786599-B2 Releasable conjugates QUIAPEG PHARMACEUTICALS AB (SE) 2023-10-17 US disclosed
WO-2007060342-A2 USE OF GUANABENZ AND ITS DERIVATIVES FOR MAKING DRUGS FOR TREATING CYSTIC FIBROSIS AND DISEASES RELATED TO A PROTEIN ADDRESSING DEFICIENCY IN THE CELLS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2007-05-31 WO disclosed
US-20070031821-A1 Screening molecules with anti-prion activity: kits, methods and screened molecules CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS ) (FR) 2007-02-08 US disclosed
EP-1551992-B1 SCREENING MOLECULES WITH ANTI-PRION ACTIVITY: KITS, METHODS AND SCREENED MOLECULES CENTRE NAT RECH SCIENT (FR) 2006-12-27 EP disclosed
US-20060172337-A1 Screening molecules with anti-prion activity: kits, methods and screened molecules CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2006-08-03 US disclosed
EP-1551992-A2 SCREENING MOLECULES WITH ANTI-PRION ACTIVITY: KITS, METHODS AND SCREENED MOLECULES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2005-07-13 EP disclosed
WO-2004035813-A2 SCREENING MOLECULES WITH ANTI-PRION ACTIVITY: KITS, METHODS AND SCREENED MOLECULES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2004-04-29 WO disclosed
EP-0985674-B1 ORGANIC COMPOUNDS CONTAINING SILICON OR GERMANIUM, TRANSITION METAL COMPLEXES, CATALYST FOR ALPHA-OLEFIN POLYMERIZATION, AND PROCESSES FOR PRODUCING ALPHA-OLEFIN POLYMERS MITSUBISHI CHEM CORP (JP) 2003-04-23 EP disclosed
US-6255515-B1 COORDINATION POLYMERIZATION CATALYSTS MITSUBISHI CHEMICAL CORPORATION (JP) 2001-07-03 US disclosed
EP-0985674-A1 ORGANIC COMPOUNDS CONTAINING SILICON OR GERMANIUM, TRANSITION METAL COMPLEXES, CATALYST FOR $g(a)-OLEFIN POLYMERIZATION, AND PROCESSES FOR PRODUCING $g(a)-OLEFIN POLYMERS MITSUBISHI CHEMICAL CORPORATION (JP) 2000-03-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230381323-A1 RELEASABLE CONJUGATES GUSB, ABCB11, UGT2B7 DCPS 271/4885KDM4E 3590/4885ALDH1A1 72/4885
US-20070031821-A1 Screening molecules with anti-prion activity: kits, methods and screened molecules ATXN2L, ATXN10, CLN6 DCPS 2702/4885KDM4E 2700/4885ALDH1A1 2586/4885
US-11786599-B2 Releasable conjugates GUSB, ABCB11, UGT2B7 DCPS 271/4885KDM4E 3590/4885ALDH1A1 72/4885
US-20240382602-A1 A CIS-PLATINUM(II)-OLIGOMER HYBRID PCNA, DCLRE1A, LIG4 DCPS 378/4885KDM4E 4861/4885ALDH1A1 2774/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.