SCHEMBL8630481

SCHEMBL8630481

Nc1ccc2c(c1)nc(N)c1ccccc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MDM4 O15151 1/20 0.47
ACHE P22303 2/20 0.46
HTR3A P46098 1/20 0.46
DHFR P00374 3/20 0.44
DCPS Q96C86 1/20 0.44
CLK1 P49759 1/20 0.44
KMT2A Q03164 4/20 0.43
MEN1 O00255 3/20 0.43
F2 P00734 1/20 0.43
LMNA P02545 1/20 0.43
CHRM2 P08172 1/20 0.43
HTR1A P08908 1/20 0.43
ADRA2A P08913 1/20 0.43
ADORA3 P0DMS8 1/20 0.43
MAOA P21397 1/20 0.43
DRD1 P21728 1/20 0.43
PTGS1 P23219 1/20 0.43
SLC6A2 P23975 1/20 0.43
SLC6A4 P31645 1/20 0.43
OPRM1 P35372 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8628496 0.86 CLK1 (0.54) ACHEHTR3ADHFRDCPSCLK1
SCHEMBL16905530 0.81 ACHE (0.49) ACHEDHFRDCPSCLK1KMT2A
SCHEMBL72801 0.81 DCPS (0.64) ACHEDCPSCLK1KMT2ALMNA
SCHEMBL29583288 0.81 DCPS (0.64) ACHEDCPSCLK1KMT2ALMNA
SCHEMBL341793 0.78 KMT2A (0.64) MDM4ACHEHTR3ADHFRKMT2A
SCHEMBL1010293 0.78 HSP90AA1 (0.49) MDM4ACHEDHFRKMT2AMEN1
SCHEMBL4947370 0.76 KMT2A (0.56) ACHEHTR3AKMT2AMEN1F2
SCHEMBL4163642 0.76 KDM4E (0.72) MDM4ACHEHTR3ADCPSKMT2A
SCHEMBL13702755 0.75 CSNK2A1 (0.65) KMT2AMEN1LMNAHTTALDH1A1
SCHEMBL6094113 0.75 DHFR (0.72) MDM4ACHEDHFRDCPSKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0614915-B1 Polymer scale preventive agent SHINETSU CHEMICAL CO (JP) 1998-06-24 EP disclosed
US-5420214-A Process to prevent scale adhesion using condensation product of a diamino heterocyclic and a quinone SHIN-ETSU CHEMICAL CO., LTD. (JP) 1995-05-30 US disclosed
EP-0614915-A1 Polymer scale preventive agent Shin-Etsu Chemical Co., Ltd. (JP) 1994-09-14 EP disclosed