Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | AGBL2 | Q5U5Z8 | 2/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.34 |
| ▸ | LOX | P28300 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | POLQ | O75417 | 2/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24424327 | 1.00 | IDO1 (0.36) | IDO1AGBL2LOXL2CACNA1HLOX | |
| SCHEMBL22016207 | 0.81 | AGBL2 (0.39) | IDO1AGBL2POLQHDAC3HDAC1 | |
| SCHEMBL16823599 | 0.79 | L3MBTL1 (0.38) | IDO1LOXL2CACNA1HLOXPRMT5 | |
| SCHEMBL2067677 | 0.79 | HTT (0.35) | IDO1LOXL2CACNA1HLOXPRMT5 | |
| SCHEMBL2084699 | 0.79 | AGBL2 (0.36) | AGBL2LOXL2CACNA1HLOXPRMT5 | |
| Hydrochloric Acid SCHEMBL16165952 | 0.78 | L3MBTL1 (0.38) | IDO1LOXL2CACNA1HLOXPRMT5 | |
| SCHEMBL357848 | 0.75 | AGBL2 (0.39) | AGBL2LOXL2PRMT5WDR77 | |
| SCHEMBL24424273 | 0.75 | CYP11B1 (0.39) | CACNA1H | |
| SCHEMBL14333743 | 0.74 | CYP11B2 (0.52) | — | |
| SCHEMBL21859472 | 0.74 | AR (0.35) | AGBL2POLQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4240736-A1 | PPAR GAMMA MODULATORS AND METHODS OF USE | Eisai R&D Management Co., Ltd. (JP) | 2023-09-13 | — | — | EP | disclosed |
| CN-116635380-A | PPARgamma modulators and methods of use | 卫材R&D管理有限公司 | 2023-08-22 | — | — | CN | disclosed |
| WO-2022099144-A1 | ΡΡΑRγ MODULATORS AND METHODS OF USE | Eisai R&D Mangement Co., Ltd. (JP) | 2022-05-12 | — | — | WO | disclosed |