Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 8/20 | 0.41 |
| ▸ | CA12 | O43570 | 7/20 | 0.41 |
| ▸ | CA1 | P00915 | 7/20 | 0.41 |
| ▸ | CA9 | Q16790 | 7/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL912857 | 1.00 | LMNA (0.56) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL912858 | 1.00 | LMNA (0.56) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL913345 | 0.90 | LMNA (0.56) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL913346 | 0.90 | LMNA (0.56) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL23253702 | 0.88 | LMNA (0.60) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL15494655 | 0.88 | LMNA (0.69) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL22927890 | 0.88 | LMNA (0.69) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL20516514 | 0.88 | LMNA (0.69) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL7147808 | 0.88 | LMNA (0.69) | LMNAKMT2APOLBALDH1A1CYP3A4 | |
| SCHEMBL11223742 | 0.88 | LMNA (0.69) | LMNAKMT2APOLBALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240261333-A1 | NOVEL TARGETS FOR ENHANCING ANTI-TUMOR IMMUNITY | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2024-08-08 | — | — | US | claimed |
| WO-2024096133-A1 | CELL-TO-CELL HTLV-1 INFECTION INHIBITOR, REMEDY FOR HTLV-1 INFECTION, REMEDY FOR HTLV-1-ASSOCIATED MYELOPATHY (HAM/TSP) | 国立大学法人 鹿児島大学 | 2024-05-10 | — | — | WO | claimed |
| WO-2022256620-A1 | NOVEL TARGETS FOR ENHANCING ANTI-TUMOR IMMUNITY | THE BROAD INSTITUTE, INC. (US) | 2022-12-08 | — | — | WO | claimed |
| US-12600740-B2 | Fluorinated N-acetyl glucosamine analogs and xylose derivatives | UTI LIMITED PARTNERSHIP (CA) | 2026-04-14 | — | — | US | disclosed |
| US-20240261333-A1 | NOVEL TARGETS FOR ENHANCING ANTI-TUMOR IMMUNITY | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2024-08-08 | — | — | US | disclosed |
| WO-2024096133-A1 | CELL-TO-CELL HTLV-1 INFECTION INHIBITOR, REMEDY FOR HTLV-1 INFECTION, REMEDY FOR HTLV-1-ASSOCIATED MYELOPATHY (HAM/TSP) | 国立大学法人 鹿児島大学 | 2024-05-10 | — | — | WO | disclosed |
| CN-116621900-B | Tetravalent platinum aminohexose complex based on regulation and control of Mucin type O-glycosylation targeting CRPC and application thereof | 河南大学 | 2024-05-07 | — | — | CN | disclosed |
| CN-114469965-B | Inhibitors of core fucosyltransferase and application thereof | 大连医科大学 | 2023-09-12 | — | — | CN | disclosed |
| CN-116621900-A | Tetravalent platinum aminohexose complex based on regulation and control of Mucin type O-glycosylation targeting CRPC and application thereof | 河南大学 | 2023-08-22 | — | — | CN | disclosed |
| WO-2022256620-A1 | NOVEL TARGETS FOR ENHANCING ANTI-TUMOR IMMUNITY | THE BROAD INSTITUTE, INC. (US) | 2022-12-08 | — | — | WO | disclosed |
| US-20220332746-A1 | FLUORINATED N-ACETYL GLUCOSAMINE ANALOGS AND XYLOSE DERIVATIVES | UTI LIMITED PARTNERSHIP (CA) | 2022-10-20 | — | — | US | disclosed |
| US-11365212-B2 | Fluorinated N-acetyl glucosamine analogs and xylose derivatives | UTI LIMITED PARTNERSHIP (CA) | 2022-06-21 | — | — | US | disclosed |
| CN-114469965-A | Inhibitor of core fucosyltransferase and application thereof | 大连医科大学 | 2022-05-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11365212-B2 | Fluorinated N-acetyl glucosamine analogs and xylose derivatives | FUT6, FUT5, B3GNT2 | LMNA 3434/4885KMT2A 2993/4885POLB 4645/4885 |
| US-20220332746-A1 | FLUORINATED N-ACETYL GLUCOSAMINE ANALOGS AND XYLOSE DERIVATIVES | CSGALNACT1, FUT6, FUT5 | LMNA 3024/4885KMT2A 3509/4885POLB 4598/4885 |
| US-12600740-B2 | Fluorinated N-acetyl glucosamine analogs and xylose derivatives | CSGALNACT1, FUT5, FUT6 | LMNA 3782/4885KMT2A 3555/4885POLB 4396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.