Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 8/20 | 0.60 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.60 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.60 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.60 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | CD44 | P16070 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3240344 | 1.00 | PNMT (0.60) | PNMTADRA2AADRA2BADRA2CDRD2 | |
| Hydrochloric Acid SCHEMBL21331206 | 0.98 | PNMT (0.58) | PNMTADRA2AADRA2BADRA2CDRD2 | |
| Hydrochloric Acid SCHEMBL29587818 | 0.98 | PNMT (0.58) | PNMTADRA2AADRA2BADRA2CDRD2 | |
| SCHEMBL1001109 | 0.92 | ASIC3 (0.60) | PNMTADRA2AADRA2BADRA2CDRD2 | |
| SCHEMBL17813307 | 0.88 | PNMT (0.47) | PNMTADRA2AADRA2BADRA2CDRD2 | |
| SCHEMBL10232037 | 0.87 | HTR2C (0.57) | PNMTADRA2AADRA2BADRA2CDRD2 | |
| SCHEMBL15957848 | 0.86 | PNMT (0.46) | PNMTADRA2AADRA2BADRA2CDRD2 | |
| SCHEMBL7216445 | 0.85 | ASIC3 (0.54) | PNMTADRA2AADRA2BADRA2CDRD2 | |
| SCHEMBL30560114 | 0.82 | CHRNB2 (0.41) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL5068876 | 0.82 | CHRNB2 (0.41) | PNMTADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122059959-A | Synthesis method and application of pyrrolo [2,1-a ] isoquinoline compound | 河南工业大学 | 2026-05-19 | — | — | CN | claimed |
| CN-115626889-B | Organic chemical conversion method for oxidative dehydrogenation of nitrogen-containing heterocyclic compound | 南京工业大学 | 2024-04-30 | — | — | CN | claimed |
| CN-122059959-A | Synthesis method and application of pyrrolo [2,1-a ] isoquinoline compound | 河南工业大学 | 2026-05-19 | — | — | CN | disclosed |
| CN-115872985-B | 1,2,3, 4-Tetrahydroisoquinoline-thiophene derivative and preparation method thereof | 赣江中药创新中心 | 2025-01-14 | — | — | CN | disclosed |
| CN-119243183-A | Synthesis method of nitrosamine organic compound | 中国科学技术大学 | 2025-01-03 | — | — | CN | disclosed |
| CN-115626889-B | Organic chemical conversion method for oxidative dehydrogenation of nitrogen-containing heterocyclic compound | 南京工业大学 | 2024-04-30 | — | — | CN | disclosed |
| CN-115626889-A | Organic chemical conversion method for oxidative dehydrogenation of nitrogen-containing heterocyclic compound | 南京工业大学 | 2023-01-20 | — | — | CN | disclosed |
| EP-4076459-A1 | PRMT5 INHIBITORS | Merck Sharp & Dohme LLC (US) | 2022-10-26 | — | — | EP | disclosed |
| CN-112939943-B | Benzimidazole compound, preparation method thereof and application of benzimidazole compound in preparation of iron death inhibitor | 中山大学 | 2022-09-16 | — | — | CN | disclosed |
| CN-109863145-B | Novel tetrahydroisoquinoline and tetrahydronaphthyridine compounds for the treatment and prevention of hepatitis b virus infection | 豪夫迈·罗氏有限公司 | 2022-04-12 | — | — | CN | disclosed |