Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GLA | P06280 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22658874 | 1.00 | L3MBTL1 (0.45) | L3MBTL1CA12CA1CA2CA7 | |
| SCHEMBL23971222 | 0.85 | L3MBTL1 (0.50) | L3MBTL1CA12CA1CA2CA7 | |
| SCHEMBL2473278 | 0.83 | NPC1 (0.43) | L3MBTL1CA12CA1CA2CA7 | |
| SCHEMBL14686821 | 0.83 | NPC1 (0.54) | L3MBTL1CA12CA1CA2CA7 | |
| SCHEMBL31020365 | 0.81 | NPC1 (0.45) | L3MBTL1CA12CA1CA2CA7 | |
| SCHEMBL22717309 | 0.81 | SMN1; SMN2 (0.45) | L3MBTL1CA12CA1CA2CA7 | |
| SCHEMBL18555299 | 0.81 | KDM4E (0.46) | L3MBTL1CA12CA1CA2CA7 | |
| SCHEMBL426998 | 0.81 | TDP1 (0.50) | L3MBTL1CA12CA1CA2CA7 | |
| SCHEMBL23970964 | 0.81 | TUBB4A (0.51) | L3MBTL1CA12CA1CA2CA7 | |
| SCHEMBL22557407 | 0.80 | L3MBTL1 (0.42) | L3MBTL1CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114391015-A | Benzo [ b ] [1,8] naphthyridineacetic acid derivatives and methods of use | 斯汀塞拉股份有限公司 | 2022-04-22 | — | — | CN | disclosed |