Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 11/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18617427 | 1.00 | CYP11B1 (0.42) | CYP11B1CYP11B2FFAR4CNR1CNR2 | |
| SCHEMBL18587952 | 0.81 | FFAR4 (0.39) | FFAR4CNR1CNR2 | |
| SCHEMBL29587648 | 0.81 | FFAR4 (0.39) | FFAR4CNR1CNR2 | |
| SCHEMBL18617452 | 0.81 | ESR1 (0.40) | CYP11B2CNR1CNR2 | |
| SCHEMBL29588509 | 0.81 | ESR1 (0.40) | CYP11B2CNR1CNR2 | |
| SCHEMBL18617502 | 0.79 | FFAR4 (0.42) | FFAR4TRPV3 | |
| SCHEMBL29588051 | 0.79 | PGR (0.46) | FFAR4 | |
| SCHEMBL18617451 | 0.79 | PGR (0.46) | FFAR4 | |
| SCHEMBL18617449 | 0.78 | CA3 (0.40) | CYP11B2CNR1CNR2 | |
| SCHEMBL29587766 | 0.78 | CA3 (0.40) | CYP11B2CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11352330-B2 | Phenoxymethyl derivatives | HOFFMANN-LA ROCHE INC. (US) | 2022-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11352330-B2 | Phenoxymethyl derivatives | CNKSR1, RB1, RCOR1 | CYP11B1 225/4885CYP11B2 419/4885FFAR4 2934/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.