Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25282083 | 0.83 | DGAT1 (0.34) | FFAR1DGAT1 | |
| SCHEMBL19626235 | 0.82 | UCHL1 (0.39) | UCHL1FFAR1DGAT1 | |
| SCHEMBL16050460 | 0.78 | UCHL1 (0.36) | UCHL1FFAR1DGAT1 | |
| SCHEMBL20085789 | 0.77 | IRAK4 (0.34) | FFAR1 | |
| SCHEMBL21858190 | 0.77 | — | — | |
| SCHEMBL1530080 | 0.77 | UCHL1 (0.38) | UCHL1FFAR1 | |
| SCHEMBL31458640 | 0.76 | UCHL1 (0.35) | UCHL1 | |
| SCHEMBL2280036 | 0.76 | LPL (0.30) | FFAR1 | |
| SCHEMBL23855378 | 0.75 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL29232852 | 0.75 | UCHL1 (0.39) | UCHL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4255429-A1 | 3-HETEROARYL PYRROLIDINE AND PIPERIDINE OREXIN RECEPTOR AGONISTS | Merck Sharp & Dohme LLC (US) | 2023-10-11 | — | — | EP | disclosed |
| WO-2022119888-A1 | 3-HETEROARYL PYRROLIDINE AND PIPERIDINE OREXIN RECEPTOR AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2022-06-09 | — | — | WO | disclosed |