Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24393966 | 0.91 | PDE2A (0.32) | PDE2A | |
| SCHEMBL29587970 | 0.87 | LMNA (0.32) | — | |
| SCHEMBL26929235 | 0.87 | PDE2A (0.36) | PDE2A | |
| SCHEMBL26929222 | 0.85 | — | — | |
| SCHEMBL26929238 | 0.85 | DRD2 (0.34) | — | |
| SCHEMBL29588742 | 0.84 | PDE2A (0.38) | PDE2A | |
| SCHEMBL24393967 | 0.82 | PDE2A (0.37) | PDE2A | |
| SCHEMBL24393969 | 0.82 | PDE2A (0.35) | PDE2A | |
| SCHEMBL25043526 | 0.81 | LMNA (0.32) | — | |
| SCHEMBL24394133 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4237408-A1 | ITACONIC ACID DERIVATIVES | Sitryx Therapeutics Limited (GB) | 2023-09-06 | — | — | EP | claimed |
| WO-2022090723-A1 | ITACONIC ACID DERIVATIVES | SITRYX THERAPEUTICS LIMITED (GB) | 2022-05-05 | — | — | WO | claimed |
| EP-4237408-A1 | ITACONIC ACID DERIVATIVES | Sitryx Therapeutics Limited (GB) | 2023-09-06 | — | — | EP | disclosed |
| WO-2022090723-A1 | ITACONIC ACID DERIVATIVES | SITRYX THERAPEUTICS LIMITED (GB) | 2022-05-05 | — | — | WO | disclosed |