⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24394126 | 0.90 | — | — | |
| SCHEMBL24394129 | 0.85 | PTGDR (0.31) | — | |
| SCHEMBL29587970 | 0.82 | LMNA (0.32) | — | |
| SCHEMBL24394132 | 0.82 | L3MBTL1 (0.33) | — | |
| SCHEMBL26929238 | 0.82 | DRD2 (0.34) | — | |
| SCHEMBL26929222 | 0.82 | — | — | |
| SCHEMBL24801183 | 0.81 | — | — | |
| SCHEMBL26941605 | 0.81 | — | — | |
| SCHEMBL29588049 | 0.80 | PDE2A (0.33) | — | |
| SCHEMBL24394237 | 0.79 | FABP4 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4237408-A1 | ITACONIC ACID DERIVATIVES | Sitryx Therapeutics Limited (GB) | 2023-09-06 | — | — | EP | claimed |
| WO-2022090723-A1 | ITACONIC ACID DERIVATIVES | SITRYX THERAPEUTICS LIMITED (GB) | 2022-05-05 | — | — | WO | claimed |
| EP-4237408-A1 | ITACONIC ACID DERIVATIVES | Sitryx Therapeutics Limited (GB) | 2023-09-06 | — | — | EP | disclosed |
| WO-2022090723-A1 | ITACONIC ACID DERIVATIVES | SITRYX THERAPEUTICS LIMITED (GB) | 2022-05-05 | — | — | WO | disclosed |
| WO-2022090723-A1 | ITACONIC ACID DERIVATIVES | SITRYX THERAPEUTICS LIMITED (GB) | 2022-05-05 | — | — | WO | disclosed |