Sugi Predict

Sugi Predict / Compounds / SCHEMBL29588066

SCHEMBL29588066

SCHEMBL29588066

C[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](N)CCCN=C(N)N)[C@@H](C)O)C(=O)O

nearest known ligand 0.68

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ OPRD1 P41143 7/20 0.68
▸ F2 P00734 1/20 0.62
▸ NTSR1 P30989 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29730557 0.88 SLC6A2 (0.59) OPRD1
SCHEMBL29386868 0.86 OPRD1 (0.82) OPRD1F2NTSR1
Analog Of Dynorphin A SCHEMBL29389694 0.84 OPRD1 (0.86) OPRD1NTSR1
Dynorphin A (1-11) SCHEMBL30132402 0.84 OPRD1 (0.86) OPRD1NTSR1
SCHEMBL29353395 0.83 SLC6A2 (0.77) OPRD1F2NTSR1
SCHEMBL29402848 0.83 SLC6A2 (0.77) OPRD1F2NTSR1
SCHEMBL30558098 0.83 SLC6A2 (0.67) OPRD1F2NTSR1
SCHEMBL29678292 0.83 KEAP1 (0.58) OPRD1
SCHEMBL31009049 0.83 OPRD1 (0.88) OPRD1NTSR1
SCHEMBL31477655 0.82 OPRD1 (0.65) OPRD1F2NTSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110612112-B insulin-FC fusions and methods of use 阿卡斯通生物科学公司 2024-03-29 — — CN disclosed
CN-116847869-A Methods and compositions for the treatment and prevention of type 1 diabetes 美商玛丽莫里斯博士联合有限责任公司 2023-10-03 — — CN disclosed
CN-115927360-B Codon-optimized insulin aspart precursor gene, recombinant vector, genetically engineered bacterium and application thereof 北京惠之衡生物科技有限公司 2023-07-14 — — CN disclosed
CN-116134046-A Methods and compositions for protein sequencing 宽腾矽公司 2023-05-16 — — CN disclosed
CN-115927360-A Codon-optimized insulin aspart precursor gene, recombinant vector, genetic engineering bacterium and application thereof 北京惠之衡生物科技有限公司 2023-04-07 — — CN disclosed
CN-115704012-A Recombinant virus containing degradation determinants and preparation method and application thereof 中国科学院深圳先进技术研究院 2023-02-17 — — CN disclosed
CN-115151273-A Methods and compositions for the treatment and prevention of type 1 diabetes 美商玛丽莫里斯博士联合有限责任公司 2022-10-04 — — CN disclosed
CN-111560379-B Codon-optimized insulin aspart precursor gene, recombinant vector, genetic engineering bacterium and application thereof 北京惠之衡生物科技有限公司 2022-09-13 — — CN disclosed
CN-114867743-A Methods of forming conjugates of sulfonamides and polypeptides 赛诺菲 2022-08-05 — — CN disclosed
CN-114423861-A Expression of modified proteins in peroxisomes 起源生物有限责任公司 2022-04-29 — — CN disclosed
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