Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 3/20 | 0.68 |
| ▸ | NOS1 | P29475 | 3/20 | 0.68 |
| ▸ | NOS2 | P35228 | 3/20 | 0.68 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | XIAP | P98170 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4558495 | 1.00 | NOS3 (0.68) | NOS3NOS1NOS2PKMSLC7A5 | |
| SCHEMBL26912720 | 1.00 | NOS3 (0.68) | NOS3NOS1NOS2PKMSLC7A5 | |
| SCHEMBL20715035 | 0.87 | NOS3 (0.56) | NOS3NOS1NOS2PKMSLC7A5 | |
| SCHEMBL8423459 | 0.87 | NOS3 (0.67) | NOS3NOS1NOS2PKMSLC7A5 | |
| SCHEMBL8423456 | 0.87 | NOS3 (0.67) | NOS3NOS1NOS2PKMSLC7A5 | |
| SCHEMBL22009906 | 0.85 | NOS3 (0.54) | NOS3NOS1NOS2MAPTALDH1A1 | |
| SCHEMBL8421337 | 0.85 | NOS3 (0.68) | NOS3NOS1NOS2PKMSLC7A5 | |
| SCHEMBL8426029 | 0.84 | NOS3 (0.64) | NOS3NOS1NOS2PKMSLC7A5 | |
| SCHEMBL8426030 | 0.81 | NOS3 (1.00) | NOS3NOS1NOS2PKMSLC7A5 | |
| SCHEMBL8423303 | 0.80 | NOS3 (0.55) | NOS3NOS1NOS2PKMSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3981784-A1 | REGULATORS OF CELL DIVISION | Technische Universität Dresden (DE) | 2022-04-13 | — | — | EP | disclosed |