Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 3/20 | 0.54 |
| ▸ | NOS1 | P29475 | 3/20 | 0.54 |
| ▸ | NOS2 | P35228 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | MDM4 | O15151 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20715035 | 0.87 | NOS3 (0.56) | NOS3NOS1NOS2L3MBTL1ALDH1A1 | |
| SCHEMBL26912720 | 0.85 | NOS3 (0.68) | NOS3NOS1NOS2L3MBTL1ALDH1A1 | |
| SCHEMBL4558495 | 0.85 | NOS3 (0.68) | NOS3NOS1NOS2L3MBTL1ALDH1A1 | |
| SCHEMBL29588178 | 0.85 | NOS3 (0.68) | NOS3NOS1NOS2L3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL31250698 | 0.78 | NOS3 (0.42) | NOS3NOS1NOS2L3MBTL1ALDH1A1 | |
| SCHEMBL24260600 | 0.78 | L3MBTL1 (0.44) | NOS3NOS1NOS2L3MBTL1ALDH1A1 | |
| SCHEMBL8029769 | 0.76 | MAPT (0.59) | ALDH1A1POLBMAPTGRIN2DGRIN3B | |
| SCHEMBL22009941 | 0.75 | ITGB3 (0.39) | MAPTGAA | |
| SCHEMBL8423456 | 0.75 | NOS3 (0.67) | NOS3NOS1NOS2L3MBTL1ALDH1A1 | |
| SCHEMBL8423459 | 0.75 | NOS3 (0.67) | NOS3NOS1NOS2L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200157144-A1 | ANTIMICROBIAL PEPTIDOMIMETICS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2020-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200157144-A1 | ANTIMICROBIAL PEPTIDOMIMETICS | NGLY1, GLMN, GMPS | NOS3 1284/4885NOS1 753/4885NOS2 1249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.