SCHEMBL20715035

SCHEMBL20715035

CC(=O)C(N)Cc1ccccc1NC(=N)N

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 3/20 0.56
NOS1 P29475 3/20 0.56
NOS2 P35228 3/20 0.56
ALDH1A1 P00352 3/20 0.40
MAPT P10636 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.39
GRIN2D O15399 1/20 0.38
GRIN3B O60391 1/20 0.38
GRIN1 Q05586 1/20 0.38
GRIN2A Q12879 1/20 0.38
GRIN2B Q13224 1/20 0.38
GRIN2C Q14957 1/20 0.38
GRIN3A Q8TCU5 1/20 0.38
SIGMAR1 Q99720 1/20 0.38
GAA P10253 2/20 0.38
TAS1R3 Q7RTX0 1/20 0.38
TAS1R1 Q7RTX1 1/20 0.38
ALPI P09923 1/20 0.37
PKM P14618 1/20 0.37
PTGS1 P23219 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22009906 0.87 NOS3 (0.54) NOS3NOS1NOS2ALDH1A1MAPT
SCHEMBL29588178 0.87 NOS3 (0.68) NOS3NOS1NOS2ALDH1A1MAPT
SCHEMBL4558495 0.87 NOS3 (0.68) NOS3NOS1NOS2ALDH1A1MAPT
SCHEMBL26912720 0.87 NOS3 (0.68) NOS3NOS1NOS2ALDH1A1MAPT
SCHEMBL8423459 0.79 NOS3 (0.67) NOS3NOS1NOS2ALDH1A1MAPT
SCHEMBL8423456 0.79 NOS3 (0.67) NOS3NOS1NOS2ALDH1A1MAPT
SCHEMBL24260601 0.78 GRIN2D (0.42) NOS3NOS1NOS2ALDH1A1MAPT
SCHEMBL8029769 0.77 MAPT (0.59) ALDH1A1MAPTGRIN2DGRIN3BGRIN1
SCHEMBL4163436 0.76 SETDB1 (0.44) NOS3NOS1NOS2ALDH1A1MAPT
SCHEMBL24260600 0.76 L3MBTL1 (0.44) NOS3NOS1NOS2ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019027366-A1 ANTIMICROBIAL PEPTIDOMIMETICS AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2019-02-07 WO disclosed