Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 8/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.75 |
| ▸ | MAPT | P10636 | 1/20 | 0.75 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TPMT | P51580 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NQO1 | P15559 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aristolochic D SCHEMBL26801941 | 1.00 | CDK2 (1.00) | CDK2MEN1KMT2AALDH1A1SMN1; SMN2 | |
| Aristolochic Acid Iv SCHEMBL29238593 | 0.90 | CDK2 (0.82) | CDK2MEN1KMT2AALDH1A1SMN1; SMN2 | |
| Aristolochic Acid SCHEMBL29518476 | 0.86 | ALDH1A1 (1.00) | CDK2MEN1KMT2AALDH1A1SMN1; SMN2 | |
| Aristolochic Acid SCHEMBL29367530 | 0.86 | ALDH1A1 (1.00) | CDK2MEN1KMT2AALDH1A1SMN1; SMN2 | |
| Aristolochic Acid SCHEMBL30825061 | 0.86 | ALDH1A1 (1.00) | CDK2MEN1KMT2AALDH1A1SMN1; SMN2 | |
| Aristolochic Acid SCHEMBL166284 | 0.86 | ALDH1A1 (1.00) | CDK2MEN1KMT2AALDH1A1SMN1; SMN2 | |
| Aristolochic Acid SCHEMBL15535358 | 0.85 | ALDH1A1 (0.98) | CDK2MEN1KMT2AALDH1A1SMN1; SMN2 | |
| 7-Hydroxy Aristolochic A SCHEMBL4557492 | 0.81 | CDK2 (1.00) | CDK2MEN1KMT2AALDH1A1SMN1; SMN2 | |
| Aristolochic Acid C SCHEMBL30039516 | 0.79 | CDK2 (1.00) | CDK2MEN1KMT2AALDH1A1SMN1; SMN2 | |
| Aristolochic Acid C SCHEMBL30697302 | 0.79 | CDK2 (1.00) | CDK2MEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116554139-B | Preparation method of reference substance of aristolochic acid D | 上海诗丹德标准技术服务有限公司 | 2025-05-06 | — | — | CN | claimed |
| WO-2024217571-A1 | METHOD FOR PREPARING REFERENCE SUBSTANCE OF ARISTOLOCHIC ACID D | 上海诗丹德标准技术服务有限公司 | 2024-10-24 | — | — | WO | claimed |
| CN-117471003-B | Separation and quantitative detection method for aristolochic acid component in houttuynia cordata and application thereof | 中国中医科学院中药研究所 | 2024-10-08 | — | — | CN | claimed |
| CN-117517537-B | Method for detecting aristolochic acid in Baicao oil based on elimination of matrix effect | 山东省食品药品检验研究院 | 2024-09-17 | — | — | CN | claimed |
| CN-117805273-B | Quantitative detection method and application of 5 aristolochic acid substances in diarrhea-relieving capsule | 浙江苏可安药业有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-117805273-A | Quantitative detection method and application of 5 aristolochic acid substances in diarrhea-relieving capsule | 浙江苏可安药业有限公司 | 2024-04-02 | — | — | CN | claimed |
| CN-117517537-A | Method for detecting aristolochic acid in Baicao oil based on elimination of matrix effect | 山东省食品药品检验研究院 | 2024-02-06 | — | — | CN | claimed |
| CN-117471003-A | Separation and quantitative detection method for aristolochic acid component in houttuynia cordata and application thereof | 中国中医科学院中药研究所 | 2024-01-30 | — | — | CN | claimed |
| US-20230372288-A1 | Application of Aristolochic Acid IVa in Preparation of Antihistamine or Drug for Treating Pneumonia | INSTITUTE OF CHINESE MATERIA MEDICA, CHINA ACADEMY OF CHINESE MEDICAL SCIENCES (CN) | 2023-11-23 | — | — | US | claimed |
| WO-2023197484-A1 | USE OF ARISTOLOCHIC ACID IVA IN PREPARING ANTIHISTAMINES OR DRUGS FOR TREATING PNEUMONIA | 中国中医科学院中药研究所 | 2023-10-19 | — | — | WO | claimed |
| CN-116554139-A | Preparation method of reference substance of aristolochic acid D | 上海诗丹德标准技术服务有限公司 | 2023-08-08 | — | — | CN | claimed |
| CN-115969840-A | Application of aristolochic acid IVa in preparing medicine for treating autoimmune disease | 上海交通大学医学院 | 2023-04-18 | — | — | CN | claimed |
| CN-113252810-B | Method for determining content of 6 aristolochic acid components in asarum | 河北省药品医疗器械检验研究院(河北省化妆品检验研究中心) | 2023-04-07 | — | — | CN | claimed |
| CN-112432990-B | Method for analyzing aristolochic acid and/or aristoloclactam | 岛津企业管理（中国）有限公司 | 2022-12-02 | — | — | CN | claimed |
| CN-114469930-B | Application of aristolochic acid IVa in preparing anti-histamine or pneumonia treatment medicine | 中国中医科学院中药研究所 | 2022-07-05 | — | — | CN | claimed |
| CN-114469930-A | Application of aristolochic acid IVa in preparing antihistaminic or pneumonia treatment medicine | 中国中医科学院中药研究所 | 2022-05-13 | — | — | CN | claimed |
| CN-116898835-B | Inhibitors of phosphodiesterase 2 activity | Changzhou University (CN) | 2026-05-26 | — | — | CN | disclosed |
| CN-116898835-B | Inhibitors of phosphodiesterase 2 activity | Changzhou University (CN) | 2026-05-26 | — | — | CN | disclosed |
| CN-114469930-A | Application of aristolochic acid IVa in preparing antihistaminic or pneumonia treatment medicine | 中国中医科学院中药研究所 | 2022-05-13 | — | — | CN | disclosed |
| CN-114469930-A | Application of aristolochic acid IVa in preparing antihistaminic or pneumonia treatment medicine | 中国中医科学院中药研究所 | 2022-05-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230372288-A1 | Application of Aristolochic Acid IVa in Preparation of Antihistamine or Drug for Treating Pneumonia | HRH4, HRH3, HRH2 | CDK2 2978/4885MEN1 4773/4885KMT2A 329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.