Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 7/20 | 1.00 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.37 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.37 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | HNF4A | P41235 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aristolochic Acid C SCHEMBL30039516 | 1.00 | CDK2 (1.00) | CDK2MEN1KMT2AMAPTALDH1A1 | |
| Aristolochic Acid Ii SCHEMBL29518307 | 0.87 | CDK2 (0.77) | CDK2MEN1KMT2AMAPTALDH1A1 | |
| Aristolochic Acid Ii SCHEMBL571697 | 0.87 | CDK2 (0.77) | CDK2MEN1KMT2AMAPTALDH1A1 | |
| Aristolochic Acid Iii SCHEMBL30568104 | 0.80 | CDK2 (1.00) | CDK2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL7456768 | 0.79 | CDK2 (0.68) | CDK2MEN1KMT2AMAPTALDH1A1 | |
| Aristolochic D SCHEMBL26801941 | 0.79 | CDK2 (1.00) | CDK2MEN1KMT2AMAPTALDH1A1 | |
| Aristolochic D SCHEMBL29588367 | 0.79 | CDK2 (1.00) | CDK2MEN1KMT2AMAPTALDH1A1 | |
| 7-Hydroxy Aristolochic A SCHEMBL4557492 | 0.76 | CDK2 (1.00) | CDK2MEN1KMT2AMAPTALDH1A1 | |
| Aristolochic Acid SCHEMBL166284 | 0.75 | ALDH1A1 (1.00) | CDK2MEN1KMT2AMAPTALDH1A1 | |
| Aristolochic Acid SCHEMBL29518476 | 0.75 | ALDH1A1 (1.00) | CDK2MEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117471003-B | Separation and quantitative detection method for aristolochic acid component in houttuynia cordata and application thereof | 中国中医科学院中药研究所 | 2024-10-08 | — | — | CN | claimed |
| CN-117517537-B | Method for detecting aristolochic acid in Baicao oil based on elimination of matrix effect | 山东省食品药品检验研究院 | 2024-09-17 | — | — | CN | claimed |
| CN-117805273-B | Quantitative detection method and application of 5 aristolochic acid substances in diarrhea-relieving capsule | 浙江苏可安药业有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-117805273-A | Quantitative detection method and application of 5 aristolochic acid substances in diarrhea-relieving capsule | 浙江苏可安药业有限公司 | 2024-04-02 | — | — | CN | claimed |
| CN-117517537-A | Method for detecting aristolochic acid in Baicao oil based on elimination of matrix effect | 山东省食品药品检验研究院 | 2024-02-06 | — | — | CN | claimed |
| CN-117471003-A | Separation and quantitative detection method for aristolochic acid component in houttuynia cordata and application thereof | 中国中医科学院中药研究所 | 2024-01-30 | — | — | CN | claimed |
| CN-117471003-B | Separation and quantitative detection method for aristolochic acid component in houttuynia cordata and application thereof | 中国中医科学院中药研究所 | 2024-10-08 | — | — | CN | disclosed |
| CN-117517537-B | Method for detecting aristolochic acid in Baicao oil based on elimination of matrix effect | 山东省食品药品检验研究院 | 2024-09-17 | — | — | CN | disclosed |
| CN-117517537-B | Method for detecting aristolochic acid in Baicao oil based on elimination of matrix effect | 山东省食品药品检验研究院 | 2024-09-17 | — | — | CN | disclosed |
| CN-117805273-B | Quantitative detection method and application of 5 aristolochic acid substances in diarrhea-relieving capsule | 浙江苏可安药业有限公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-117805273-A | Quantitative detection method and application of 5 aristolochic acid substances in diarrhea-relieving capsule | 浙江苏可安药业有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-117517537-A | Method for detecting aristolochic acid in Baicao oil based on elimination of matrix effect | 山东省食品药品检验研究院 | 2024-02-06 | — | — | CN | disclosed |
| CN-117517537-A | Method for detecting aristolochic acid in Baicao oil based on elimination of matrix effect | 山东省食品药品检验研究院 | 2024-02-06 | — | — | CN | disclosed |
| CN-117471003-A | Separation and quantitative detection method for aristolochic acid component in houttuynia cordata and application thereof | 中国中医科学院中药研究所 | 2024-01-30 | — | — | CN | disclosed |