Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 17/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 17/20 | 0.57 |
| ▸ | BCL2 | P10415 | 2/20 | 0.55 |
| ▸ | HRH2 | P25021 | 4/20 | 0.52 |
| ▸ | HTR2C | P28335 | 4/20 | 0.52 |
| ▸ | HRH1 | P35367 | 4/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.52 |
| ▸ | HTR1A | P08908 | 3/20 | 0.52 |
| ▸ | HTR2A | P28223 | 3/20 | 0.52 |
| ▸ | HTR2B | P41595 | 3/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.52 |
| ▸ | HTR5A | P47898 | 1/20 | 0.52 |
| ▸ | HTR1E | P28566 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29589992 | 0.94 | TMEM97 (0.53) | TMEM97SIGMAR1BCL2HRH2HTR2C | |
| SCHEMBL29589794 | 0.86 | BCL2 (0.57) | BCL2 | |
| SCHEMBL29590139 | 0.84 | NR1H2 (0.56) | BCL2 | |
| SCHEMBL29590765 | 0.83 | BCL2 (0.58) | TMEM97SIGMAR1BCL2 | |
| SCHEMBL16416972 | 0.82 | HSP90AA1 (0.47) | — | |
| SCHEMBL29590466 | 0.82 | HSP90AA1 (0.47) | — | |
| SCHEMBL29590775 | 0.82 | HSP90AA1 (0.47) | — | |
| SCHEMBL1793928 | 0.81 | TMEM97 (0.67) | TMEM97SIGMAR1HRH2HTR2CHRH1 | |
| SCHEMBL29589933 | 0.81 | BCL2 (0.54) | BCL2 | |
| SCHEMBL29591192 | 0.80 | BCL2 (0.51) | BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109456324-B | Isoindoline or isoquinoline compounds, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2022-04-22 | — | — | CN | disclosed |