Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 18/20 | 0.54 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29589794 | 0.92 | BCL2 (0.57) | BCL2ACHE | |
| SCHEMBL29589838 | 0.88 | HPGD (0.56) | BCL2ACHE | |
| SCHEMBL29589716 | 0.87 | BCL2 (0.56) | BCL2 | |
| SCHEMBL29589723 | 0.86 | BCL2 (0.52) | BCL2 | |
| SCHEMBL29590813 | 0.85 | BCL2 (0.55) | BCL2 | |
| SCHEMBL29590139 | 0.84 | NR1H2 (0.56) | BCL2NR1H2 | |
| SCHEMBL29590775 | 0.84 | HSP90AA1 (0.47) | — | |
| SCHEMBL29590466 | 0.82 | HSP90AA1 (0.47) | — | |
| SCHEMBL16416972 | 0.82 | HSP90AA1 (0.47) | — | |
| SCHEMBL28052547 | 0.81 | LIPE (0.56) | NR1H2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109456324-B | Isoindoline or isoquinoline compounds, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2022-04-22 | — | — | CN | disclosed |