Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 15/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 15/20 | 0.53 |
| ▸ | HRH1 | P35367 | 5/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.53 |
| ▸ | HRH2 | P25021 | 4/20 | 0.53 |
| ▸ | HTR1A | P08908 | 3/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.53 |
| ▸ | HTR2C | P28335 | 2/20 | 0.53 |
| ▸ | HTR2B | P41595 | 2/20 | 0.53 |
| ▸ | DRD1 | P21728 | 1/20 | 0.53 |
| ▸ | HTR1B | P28222 | 1/20 | 0.53 |
| ▸ | HTR1E | P28566 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | BCL2 | P10415 | 2/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29589768 | 0.94 | TMEM97 (0.57) | TMEM97SIGMAR1HRH1HRH3HRH2 | |
| SCHEMBL29589723 | 0.85 | BCL2 (0.52) | BCL2 | |
| SCHEMBL29589765 | 0.83 | BCL2 (0.49) | BCL2 | |
| SCHEMBL29590004 | 0.83 | BCL2 (0.59) | TMEM97SIGMAR1HRH1HRH3HRH2 | |
| SCHEMBL1690517 | 0.82 | NPSR1 (0.56) | HTR2CNPSR1PTPN1 | |
| SCHEMBL18970283 | 0.82 | NPSR1 (0.56) | HTR2CNPSR1PTPN1 | |
| SCHEMBL29589757 | 0.82 | BCL2 (0.42) | BCL2 | |
| SCHEMBL29590813 | 0.80 | BCL2 (0.55) | BCL2 | |
| SCHEMBL29590949 | 0.80 | NAMPT (0.42) | BCL2 | |
| SCHEMBL29589831 | 0.80 | OPRM1 (0.43) | BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109456324-B | Isoindoline or isoquinoline compounds, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2022-04-22 | — | — | CN | disclosed |