Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | BCL2 | P10415 | 13/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29589794 | 0.90 | BCL2 (0.57) | BCL2ACHE | |
| SCHEMBL29589933 | 0.88 | BCL2 (0.54) | BCL2ACHE | |
| SCHEMBL29589716 | 0.85 | BCL2 (0.56) | BCL2RAB9ASMN1; SMN2 | |
| SCHEMBL29589723 | 0.84 | BCL2 (0.52) | BCL2MEN1KMT2AMAPT | |
| SCHEMBL29590813 | 0.83 | BCL2 (0.55) | BCL2 | |
| SCHEMBL8247508 | 0.82 | HPGD (0.68) | HPGDMEN1KMT2ARAB9AFAAH | |
| SCHEMBL29698174 | 0.82 | HPGD (0.68) | HPGDMEN1KMT2ARAB9AFAAH | |
| SCHEMBL29590139 | 0.82 | NR1H2 (0.56) | BCL2LMNA | |
| SCHEMBL29590466 | 0.80 | HSP90AA1 (0.47) | HPGDMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL29590775 | 0.80 | HSP90AA1 (0.47) | HPGDMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109456324-B | Isoindoline or isoquinoline compounds, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2022-04-22 | — | — | CN | disclosed |