Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | FAAH | O00519 | 3/20 | 0.60 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | MGLL | Q99685 | 3/20 | 0.58 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8247508 | 1.00 | HPGD (0.68) | HPGDMEN1KMT2ARAB9AFAAH | |
| SCHEMBL31597009 | 0.92 | MGLL (0.60) | HPGDMEN1KMT2ARAB9AFAAH | |
| SCHEMBL13647708 | 0.90 | HPGD (0.54) | HPGDMEN1KMT2ARAB9AFAAH | |
| SCHEMBL15355311 | 0.84 | SMN1; SMN2 (0.59) | HPGDMEN1KMT2ARAB9AFAAH | |
| SCHEMBL29589853 | 0.84 | SMN1; SMN2 (0.59) | HPGDMEN1KMT2ARAB9AFAAH | |
| SCHEMBL29589838 | 0.82 | HPGD (0.56) | HPGDMEN1KMT2ARAB9AFAAH | |
| SCHEMBL28826015 | 0.82 | LIPE (0.62) | HPGDMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL29591000 | 0.82 | RAB9A (0.59) | HPGDMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL29560919 | 0.82 | L3MBTL1 (0.66) | HPGDMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL28052547 | 0.82 | LIPE (0.56) | HPGDMEN1KMT2ARAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332873-A | Protein tyrosine phosphatase inhibitors and methods of use thereof | 卡里科生命科学有限责任公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-114025844-B | Protein tyrosine phosphatase inhibitors and methods of use thereof | 卡里科生命科学有限责任公司 | 2022-07-26 | — | — | CN | disclosed |