SCHEMBL29590556

SCHEMBL29590556

NC(=O)C[C@H](NC(=O)CNC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](N)Cc1c[nH]cn1)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ OPRD1 P41143 10/20 0.39
▸ OPRM1 P35372 9/20 0.39
▸ OPRK1 P41145 3/20 0.39
▸ F2 P00734 4/20 0.35
▸ MEN1 O00255 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ ECE1 P42892 1/20 0.33
▸ BACE1 P56817 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29630620 0.99 OPRD1 (0.38) OPRD1OPRM1OPRK1F2MEN1
SCHEMBL29590467 0.90 GRPR (0.39) OPRD1OPRM1OPRK1F2
SCHEMBL32677418 0.89 SLC15A2 (0.43) F2
SCHEMBL29373629 0.89 ECE1 (0.39) MEN1KMT2AECE1BACE1
SCHEMBL30192164 0.88 BACE1 (0.36) ECE1BACE1
SCHEMBL30504749 0.87 OPRM1 (0.36) OPRD1OPRM1OPRK1F2
SCHEMBL31590090 0.87 OPRD1 (0.35) OPRD1OPRM1OPRK1F2MEN1
SCHEMBL11028917 0.86 OPRD1 (0.37) OPRD1OPRM1OPRK1
SCHEMBL11028909 0.86 OPRD1 (0.37) OPRD1OPRM1OPRK1
SCHEMBL29592282 0.86 OPRD1 (0.42) OPRD1OPRM1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12618102-B2 Biochemical reaction methods and reagents comprising intrinsically disordered regions Biocrucible Limited (GB) 2026-05-05 — — US disclosed
US-20220112547-A1 BIOCHEMICAL REACTION METHODS AND REAGENTS COMPRISING INTRINSICALLY DISORDERED REGIONS Biocrucible Limited (GB) 2022-04-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12618102-B2 Biochemical reaction methods and reagents comprising intrinsically disordered regions POLM, POLR1A, POLR1E OPRD1 4566/4885OPRM1 4101/4885OPRK1 4730/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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