Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTK1 | Q9Y2Q3 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | PPARG | P37231 | 6/20 | 0.50 |
| ▸ | PPARD | Q03181 | 6/20 | 0.50 |
| ▸ | PPARA | Q07869 | 6/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5973366 | 1.00 | GSTK1 (0.55) | GSTK1TSHRLMNANFKB1PMP22 | |
| SCHEMBL14685943 | 1.00 | GSTK1 (0.55) | GSTK1TSHRLMNANFKB1PMP22 | |
| SCHEMBL11254501 | 1.00 | GSTK1 (0.55) | GSTK1TSHRLMNANFKB1PMP22 | |
| SCHEMBL14686086 | 1.00 | GSTK1 (0.55) | GSTK1TSHRLMNANFKB1PMP22 | |
| SCHEMBL8359558 | 1.00 | GSTK1 (0.55) | GSTK1TSHRLMNANFKB1PMP22 | |
| SCHEMBL1198436 | 1.00 | GSTK1 (0.55) | GSTK1TSHRLMNANFKB1PMP22 | |
| SCHEMBL7621946 | 0.98 | GSTK1 (0.54) | GSTK1TSHRLMNANFKB1PMP22 | |
| SCHEMBL868777 | 0.91 | — | — | |
| SCHEMBL4899440 | 0.83 | GSTK1 (0.52) | GSTK1TSHRLMNANFKB1PMP22 | |
| SCHEMBL2722834 | 0.81 | TSHR (0.60) | GSTK1TSHRLMNANFKB1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7763475-B2 | Measurement and use of molecular interactions | INVERNESS MEDICAL SWITZERLAND GMBH (CH) | 2010-07-27 | — | — | US | disclosed |
| US-20100044673-A1 | LABELING FLUORESCENT COMPOUND | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2010-02-25 | — | — | US | disclosed |
| US-20070218534-A1 | Measurement and use of molecular interactions | Abbott Rapid Diagnostics International Unlimited Company (IE) | 2007-09-20 | — | — | US | disclosed |
| US-7195909-B2 | Measurement and use of molecular interactions | AKUBIO LIMITED (GB) | 2007-03-27 | — | — | US | disclosed |
| EP-1171769-B1 | MEASUREMENT AND USE OF MOLECULAR INTERACTIONS | AKUBIO LTD (GB) | 2004-09-29 | — | — | EP | disclosed |
| US-20030194697-A1 | Measurement and use of molecular interactions | Abbott Rapid Diagnostics International Unlimited Company (IE) | 2003-10-16 | — | — | US | disclosed |
| US-6589727-B1 | Determining binding affinity between two partners where one is immobilized on a surface; oscillating the surface to cause dissociation; detection by acoustic emission | AKUBIO LTD. (GB) | 2003-07-08 | — | — | US | disclosed |
| EP-1171769-A1 | MEASUREMENT AND USE OF MOLECULAR INTERACTIONS | Akubio Limited (GB) | 2002-01-16 | — | — | EP | disclosed |
| WO-2001002857-A1 | MEASUREMENT AND USE OF MOLECULAR INTERACTIONS | AKUBIO LIMITED (GB) | 2001-01-11 | — | — | WO | disclosed |