Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTK1 | Q9Y2Q3 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 6/20 | 0.46 |
| ▸ | PPARD | Q03181 | 6/20 | 0.46 |
| ▸ | PPARA | Q07869 | 6/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14685943 | 0.83 | GSTK1 (0.55) | GSTK1TSHRFFAR4FFAR1LMNA | |
| SCHEMBL11254501 | 0.83 | GSTK1 (0.55) | GSTK1TSHRFFAR4FFAR1LMNA | |
| SCHEMBL14686086 | 0.83 | GSTK1 (0.55) | GSTK1TSHRFFAR4FFAR1LMNA | |
| SCHEMBL8359558 | 0.83 | GSTK1 (0.55) | GSTK1TSHRFFAR4FFAR1LMNA | |
| SCHEMBL1198436 | 0.83 | GSTK1 (0.55) | GSTK1TSHRFFAR4FFAR1LMNA | |
| SCHEMBL2959092 | 0.83 | GSTK1 (0.55) | GSTK1TSHRFFAR4FFAR1LMNA | |
| SCHEMBL5973366 | 0.83 | GSTK1 (0.55) | GSTK1TSHRFFAR4FFAR1LMNA | |
| SCHEMBL7621946 | 0.80 | GSTK1 (0.54) | GSTK1TSHRFFAR4FFAR1LMNA | |
| SCHEMBL31051586 | 0.78 | ENPEP (0.47) | GSTK1TSHRLMNANFKB1PMP22 | |
| SCHEMBL9405656 | 0.78 | TSHR (0.60) | TSHRFFAR4FFAR1LMNANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9107889-B2 | Compositions comprising an NO donor and a dithiolane and their use for improvement of sexual function | ENCRYPTA GMBH (DE) | 2015-08-18 | — | — | US | disclosed |
| US-20080161381-A1 | Improving nitric oxide (NO) availability; such as arginine and alpha lipoic acid; treats wide range of physical and psychological dysfunctions | EXTARMA AG (CH) | 2008-07-03 | — | — | US | disclosed |
| EP-1909782-A2 | COMPOSITIONS COMPRISING AN NO DONOR AND A DITHIOLANE AND THEIR USE FOR IMPROVEMENT OF SEXUAL FUNCTION | Extarma AG (CH) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007017191-A2 | COMPOSITIONS COMPRISING AN NO DONOR AND A DITHIOLANE AND THEIR USE FOR IMPROVEMENT OF SEXUAL FUNCTION | EXTARMA AG (CH) | 2007-02-15 | — | — | WO | disclosed |