SCHEMBL2959158

SCHEMBL2959158

Cn1c(-c2ccc(CBr)cc2)noc1=O

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.43
HTT P42858 1/20 0.43
MAPT P10636 1/20 0.36
CMA1 P23946 1/20 0.36
KMT2A Q03164 3/20 0.35
MEN1 O00255 2/20 0.35
TSHR P16473 1/20 0.35
DCTPP1 Q9H773 2/20 0.33
HSD11B1 P28845 2/20 0.33
KCNJ1 P48048 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
PLA2G2A P14555 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13201426 0.85 ALDH1A1 (0.43) ALDH1A1HTTMAPTCMA1KMT2A
SCHEMBL27930459 0.84 ALDH1A1 (0.43) ALDH1A1HTTMAPTCMA1KMT2A
SCHEMBL24483836 0.81 MAPT (0.42) ALDH1A1HTTMAPTCMA1KMT2A
SCHEMBL10151243 0.78 KMT2A (0.49) ALDH1A1KMT2AMEN1TSHR
SCHEMBL20168365 0.74 DGAT1 (0.36) ALDH1A1HTTMAPTCMA1KMT2A
SCHEMBL24469892 0.74 CA2 (0.38) ALDH1A1HTTMAPTCMA1KMT2A
SCHEMBL24483834 0.70 KMT2A (0.35) ALDH1A1HTTMAPTCMA1KMT2A
SCHEMBL2284851 0.67 MAPT (0.36) MAPTCMA1KMT2A
SCHEMBL26581745 0.66 NR4A2 (0.34) ALDH1A1MAPTCMA1
SCHEMBL19857608 0.65 BRD4 (0.68)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1445249-B1 NOVEL BENSOPHENONE DERIVATIVES OR SALTS THEREOF TOYAMA CHEMICAL CO LTD (JP) 2012-11-07 EP disclosed
US-7772285-B2 Benzophenone derivatives or salts thereof TOYAMA CHEMICAL CO., LTD. (JP) 2010-08-10 US disclosed
EP-1445249-A1 NOVEL BENSOPHENONE DERIVATIVES OR SALTS THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2004-08-11 EP disclosed