Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 10/20 | 0.46 |
| ▸ | F11 | P03951 | 3/20 | 0.39 |
| ▸ | TPSB2 | P20231 | 2/20 | 0.39 |
| ▸ | PLAU | P00749 | 2/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.34 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.32 |
| ▸ | MPO | P05164 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29852507 | 1.00 | CFD (0.46) | CFDF11TPSB2PLAUKLKB1 | |
| SCHEMBL23218209 | 1.00 | CFD (0.46) | CFDF11TPSB2PLAUKLKB1 | |
| SCHEMBL29853113 | 0.91 | CFD (0.47) | CFDF11TPSB2PLAUKLKB1 | |
| SCHEMBL23218969 | 0.91 | CFD (0.47) | CFDF11TPSB2PLAUKLKB1 | |
| SCHEMBL29592635 | 0.91 | CFD (0.47) | CFDF11TPSB2PLAUKLKB1 | |
| SCHEMBL23219197 | 0.87 | TBXAS1 (0.37) | CFDTBXAS1L3MBTL1SYK | |
| SCHEMBL29852344 | 0.87 | TBXAS1 (0.37) | CFDTBXAS1L3MBTL1SYK | |
| SCHEMBL23219213 | 0.86 | CFD (0.47) | CFDF11TPSB2PLAUKLKB1 | |
| SCHEMBL29591255 | 0.86 | CFD (0.47) | CFDF11TPSB2PLAUKLKB1 | |
| SCHEMBL23218210 | 0.86 | CFD (0.44) | CFDF11TPSB2PLAUKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114502168-A | Oral complement factor D inhibitors | 拜奥克里斯特制药公司 | 2022-05-13 | — | — | CN | disclosed |