Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | CFD | P00746 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | TTK | P33981 | 1/20 | 0.33 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.33 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29852344 | 1.00 | TBXAS1 (0.37) | TBXAS1CFDL3MBTL1TTKSLC16A3 | |
| SCHEMBL29852507 | 0.87 | CFD (0.46) | TBXAS1CFDL3MBTL1SYK | |
| SCHEMBL29592602 | 0.87 | CFD (0.46) | TBXAS1CFDL3MBTL1SYK | |
| SCHEMBL23218209 | 0.87 | CFD (0.46) | TBXAS1CFDL3MBTL1SYK | |
| SCHEMBL29852450 | 0.83 | TBXAS1 (0.41) | TBXAS1CFDL3MBTL1SLC16A3SLC16A1 | |
| SCHEMBL23219068 | 0.83 | TBXAS1 (0.41) | TBXAS1CFDL3MBTL1SLC16A3SLC16A1 | |
| SCHEMBL23219204 | 0.83 | L3MBTL1 (0.36) | TBXAS1CFDL3MBTL1DHFR | |
| SCHEMBL28736110 | 0.78 | CFD (0.40) | TBXAS1CFDL3MBTL1PDK2SYK | |
| SCHEMBL23218969 | 0.76 | CFD (0.47) | CFDL3MBTL1 | |
| SCHEMBL29592635 | 0.76 | CFD (0.47) | CFDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114502168-A | Oral complement factor D inhibitors | 拜奥克里斯特制药公司 | 2022-05-13 | — | — | CN | disclosed |
| WO-2021072198-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |
| WO-2021072198-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |