Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | UNG | P13051 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 8/20 | 0.45 |
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL313874 | 0.84 | TDP1 (0.65) | MAOAMAOBUNGSLC6A2SLC6A3 | |
| SCHEMBL2223288 | 0.77 | SMN1; SMN2 (0.57) | UNGKMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14570073 | 0.77 | MAPT (0.54) | SLC6A2SLC6A3KMT2ATDP1RAB9A | |
| SCHEMBL16217665 | 0.77 | UNG (0.47) | UNGRAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL11761107 | 0.74 | ALDH1A1 (0.62) | SLC6A2SLC6A3KMT2ATDP1RAB9A | |
| SCHEMBL29592341 | 0.74 | ALDH1A1 (0.62) | SLC6A2SLC6A3KMT2ATDP1RAB9A | |
| SCHEMBL16217649 | 0.74 | UNG (0.43) | UNGRAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL12744030 | 0.73 | TDP1 (0.50) | SLC6A2SLC6A3KMT2ATDP1RAB9A | |
| SCHEMBL29733178 | 0.73 | MAOA (0.51) | MAOAMAOBKMT2AALDH1A1LMNA | |
| SCHEMBL321579 | 0.72 | LMNA (0.51) | MAOBSLC6A2SLC6A3KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022047008-A1 | HSP90-BINDING CONJUGATES AND FORMULATIONS THEREOF | TARVEDA THERAPEUTICS, INC. (US) | 2022-03-03 | — | — | WO | disclosed |